Extraction-free cortisol assay

Details Extraction-free cortisol assay Extraction-free cortisol assay

1977-07-05

1978-12-05

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 424 12, G01N 3316

Patent

active

041286294

ABSTRACT:
Immobilization of active anti-cortisol antibodies onto negatively charged solid phase surfaces results in a shift of the antibody pH optimum to an acidic range thereby permitting effective yet minimal use of deblocking agents and an extraction-free immunoassay for cortisol.

REFERENCES:
patent: 4034073 (1977-07-01), Weetall
Brombacher et al., Journal of Endocrinology, vol. 72, No. 1, Jan. 1977, p. 57P.
Tilden, Clinical Chemistry, vol. 23, No. 2, Feb. 1977, pp. 211-215.
Farmer et al., Clinical Chemistry, vol. 20, No. 4, Apr. 1974, pp. 411-414.
Foster et al., Clinical Chemistry, vol. 20, No. 3, Mar. 1974, pp. 365-368.

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