Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1994-12-12
1996-08-20
Fleisher, Mindy
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 934, 424 9348, 4352523, 4352528, A61K 3908, A61K 3910, A61K 39112, C12N 121
Patent
active
055476643
ABSTRACT:
The invention concerns a vaccine comprising an attenuated Salmonella bacterium which contains a nirB promoter operably linked to a DNA sequence encoding a heterologous protein. The nirB promoter directs expression of the heterologous protein in a host it is wished to vaccinate.
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Charles Ian G.
Chatfield Steven N.
Fairweather Neil F.
Burroughs Wellcome Co.
Carter Philip W.
Fleisher Mindy
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