Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-03-26
1997-12-30
Fleisher, Mindy
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 697, 435 698, 43525233, 4353201, C12P 2102, C12N 1570, C12N 1571, C12N 121
Patent
active
057029210
ABSTRACT:
The present invention relates to a plasmid possessing the restriction enzyme map shown in FIG. 1 , and this plasmid is largely characterized in that the kil gene is linked downstream from the human CRP (C-reactive protein) gene. Using this plasmid, it is possible to produce large amounts of human CRP by extracellular secretion.
REFERENCES:
patent: 5246839 (1993-09-01), Horikoshi et al.
patent: 5547931 (1996-08-01), Potempa
M. L. Tenchini et al, "Comparison of sequence of cDNA clone with other genomic and cDNA sequences for human C-reactive protein", Inflammation, Vol. 16, No. 2, Apr. 1992, pp. 93-99.
C. Toniatti et al, "Synergistic trans-activation of the human C-reactive protein promoter by transcription factor HNF-1 binding at two distinct sites", J. EMBO, Vol. 9, No. 13, Dec. 1990, pp. 4467-4475.
"Expression in Escherichia coli of a Chemically Synthesized Gene for the Hormone Somatostatin", Science, Vol. 198, pp. 1056-1063 (1978).
"Preparation of Transforming Deoxyribonucleic Acid by Phenol Treatment", Biochimica et Biophysica ACTA, Vol. 72, No. 4, pp. 619-629 (1963).
"Ligation of EcoRl Endonuclease-generated DNA Fragments into Linear and Circular Structures", Journal of Molecular Biology, Vol. 96, pp. 171-184, (1974).
Abstract of: Protein, Nucleic Acid and Enzyme, Vol. 29, pp. 294-306 (1986).
"Calcium-Dependent Bacteriophage DNA Infection", Journal of Molecular Biology, Vol. 53, pp. 159-162 (1970).
"Sequence Diversity among Related Genes for Recognition of Specific Targets in DNA Molecules", Journal of Molecular Biology, Vol. 166, pp. 1-19 (1983).
"One-step Preparation of Competent Escherichia coli:Transformation and Storage of Bacterial Cells in the Same Solution", Proc. Natl. Acad. Sci. USA, Vol. 86, pp. 2172-2175 (1989).
Lei et al, J. of Biol. Chem. 260(24), pp. 13377-13383, Oct. 1985.
Woo et al, J. of Biol. Chem. 260(24), pp. 13384-13388, Oct. 1985.
Sambrook et al., Molecular Cloning: A laboratory manual, pp. 1.74-1.81;pp. 17.10-17.11, 1989.
Oka et al., PNAS (USA) 82, pp. 7212-7216, Nov. 1985.
Kobayashi et al., J. of Bacteriology 166(3), pp. 728-732, Jun. 1986.
Fleisher Mindy
McKelvey Terry A.
Orienta Yeast Co., Ltd.
LandOfFree
Expression of biologically active human C-reactive protein in es does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Expression of biologically active human C-reactive protein in es, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Expression of biologically active human C-reactive protein in es will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-201475