Esters

Details Esters Esters

1980-03-14

1982-07-20

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

544265, 424253, C07D47330

Patent

active

043407269

ABSTRACT:
There are prepared compounds of the formula ##STR1## where R.sup.1 is alkyl of 1 to 8 carbon atoms and R.sup.2 is the ester group of an unsubstituted monocarboxylic acid, aromatic carboxylic acid, aminocarboxylic acid, unsubstituted dicarboxylic acid, phosphoric acid, or nitric acid or a glycoside or an acetaldehyde acetal. The compounds are immunomodulators, have antiviral activity and antitumor activity and also are enzyme inhibitors. The compounds can also be used to introduce the corresponding alcohol into biological systems, in some cases with enhanced potency.

REFERENCES:
patent: 3862189 (1975-01-01), Schwender
patent: 4138562 (1979-02-01), Vince
patent: 4151277 (1979-04-01), Albrecht
patent: 4221794 (1980-09-01), Simon et al.
patent: 4221909 (1980-09-01), Simon et al.
patent: 4221910 (1980-09-01), Giner-Sorolla
patent: 4321376 (1982-03-01), Otani et al.
Sinkula, Annual Reports in Medicinal Chemistry, vol. 10, pp. 306-316, 1975.
Yoshikawa, Bull. of Chem. Soc., rf, Japan, vol. 62, pp. 3505-3508, (1969).

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