Enhanced waveguide and method

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

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C422S051000, C422S051000, C422S051000, C422S063000, C422S082050, C422S082080, C422S082110, C435S287200, C435S287300, C435S287900, C435S288700, C435S808000, C436S043000, C436S047000, C436S164000, C436S172000, C436S518000, C436S524000, C436S527000, C436S805000

Reexamination Certificate

active

10470216

ABSTRACT:
The present invention provides an optical assay apparatus that includes a light source module and an optical sensor. The light source module produces light having a range of propagation angles. The sensor includes a light adjusting portion and an assay sensing portion. The light adjusting portion receives the light produced by the light source module and provides light having a propagation angle that is substantially constant to the assay sensing portion. In one embodiment, the sensor may be coupled with the light source module by an interrogation module which includes a window in which a waveguide is integrated. In another embodiment, the sensor and interrogation module are mounted in an automated assay platform that provides two-dimensional or three-dimensional movement of the sensor so that it can be sequentially immersed in solutions required to perform a particular assay protocol. While the sensor is immersed in a particular liquid, the system provides oscillatory movement of the sensor and/or rotary movement of the contacted liquid to increase evanescent wave region reaction rates with targeted analytes and/or reagents.

REFERENCES:
patent: 3604927 (1971-09-01), Hirschfeld
patent: 4050895 (1977-09-01), Hardy et al.
patent: 4133639 (1979-01-01), Harte
patent: 4257671 (1981-03-01), Barbaudy et al.
patent: 4321057 (1982-03-01), Buckles
patent: 4399099 (1983-08-01), Buckles
patent: 4447546 (1984-05-01), Hirschfeld
patent: 4477578 (1984-10-01), Miles et al.
patent: 4558014 (1985-12-01), Hirschfeld et al.
patent: 4582809 (1986-04-01), Block et al.
patent: 4595833 (1986-06-01), Sting
patent: 4654532 (1987-03-01), Hirschfeld
patent: 4671938 (1987-06-01), Cook
patent: 4716121 (1987-12-01), Block et al.
patent: 4844869 (1989-07-01), Glass
patent: 4852967 (1989-08-01), Cook et al.
patent: 4909990 (1990-03-01), Block et al.
patent: 5055408 (1991-10-01), Higo et al.
patent: 5061857 (1991-10-01), Thompson et al.
patent: 5093569 (1992-03-01), Krumboltz et al.
patent: 5111221 (1992-05-01), Fare et al.
patent: 5152962 (1992-10-01), Lackie
patent: 5156976 (1992-10-01), Slovacek et al.
patent: 5225374 (1993-07-01), Fare et al.
patent: 5242797 (1993-09-01), Hirschfeld
patent: 5268486 (1993-12-01), Waggoner et al.
patent: 5290398 (1994-03-01), Feldman et al.
patent: 5340715 (1994-08-01), Slovacek et al.
patent: 5359681 (1994-10-01), Jorgenson et al.
patent: 5399866 (1995-03-01), Feldman et al.
patent: 5430813 (1995-07-01), Anderson et al.
patent: 5442448 (1995-08-01), Knoll
patent: 5468606 (1995-11-01), Bogart et al.
patent: 5492674 (1996-02-01), Meserol
patent: 5494793 (1996-02-01), Schindele et al.
patent: 5512492 (1996-04-01), Herron et al.
patent: 5525466 (1996-06-01), Slovacek et al.
patent: 5545517 (1996-08-01), Thompson et al.
patent: 5569766 (1996-10-01), Waggoner et al.
patent: 5582796 (1996-12-01), Carey et al.
patent: 5719063 (1998-02-01), Block
patent: 5858800 (1999-01-01), Shigemori et al.
patent: 5885529 (1999-03-01), Babson et al.
patent: 6007996 (1999-12-01), McNamara et al.
patent: 6008057 (1999-12-01), Glass et al.
patent: 6110749 (2000-08-01), Obremski et al.
patent: 6136611 (2000-10-01), Saaski et al.
patent: 6192168 (2001-02-01), Feldstein et al.
patent: 0 128 723 (1984-12-01), None
patent: 0 535 690 (1993-04-01), None
patent: S63-273042 (1988-11-01), None
patent: H02-191674 (1990-07-01), None
patent: H03-272466 (1991-12-01), None
patent: H04-225144 (1992-08-01), None
patent: H05-118991 (1993-05-01), None
patent: H05-203574 (1993-08-01), None
patent: H06-308031 (1994-11-01), None
patent: H07-063756 (1995-03-01), None
patent: H07-103901 (1995-04-01), None
patent: H07-174692 (1995-07-01), None
patent: H07-181132 (1995-07-01), None
patent: H07-318481 (1995-12-01), None
patent: H09-257806 (1997-10-01), None
patent: 2000-171391 (2000-06-01), None
patent: 2000-325295 (2000-11-01), None
patent: 2000-356585 (2000-12-01), None
patent: WO 84/00817 (1984-03-01), None
patent: WO 90 09574 (1990-08-01), None
patent: WO 92/08966 (1992-05-01), None
patent: WO9531711 (1995-11-01), None
Li Li, C. et al., “Application of Electromodulated Fluorescence To The . . . ”, Langmuir 2000, vol. 16, No. 10, pp. 4672-4677, American Chemical Society, U.S., 2000.
Anderson, George P. et al., “A Fiber Optic Biosensor: Combination Tapered Fibers Designed For Improved Signal . . . ”, Bio-Sensors & Bioelectronics 8:249-256, 1993.
Anis, N.A., et al., “A Fiber-Optic Immunosensor For Detecting Parathion”, Analytical Letters 25(4):627-635, 1992.
Gao, Harry H. et al., “Tapered Fiber Tips For Fiber Optic Biosensors”, Optical Engineering 34(12):3465-3470, 1995.
Glass, Thomas R., et al, “Effect Of Numerical Aperture On Signal Level In Cylindrical Waveguide Evanescent Fluorosensors”, Applied Optics 26(11):2181-2187, 1987.
Golden, Joel P. et al., “Fluorometer And Tapered Fiber optic Probes For Sensing In The Evanscent Wave”, Optical Engineering 31(7):1458-1462, 1992.
Golden, Joel P. et al., “Portable Multichannel Fiber Optic Biosensor For Field Detection”, 1997 Optical Engineering 36(4), 1008-1013, Apr. 1997.
Golden, Joel P. et al., “Ray Tracing Determination Of Evanescent Wave Penetration Depth . . . ”, Chemical, Biochemical, and Environmental Fiber Sensors IV 1796:9-13, 1992.
Hale, Z.M., et al., “Fluorescent Sensors Based On Tapered Single-Mode Optical Fibers”, Sensors And Actuators B. 17:233-240, 1994.
Hobbs, J.R., “Fluorescence Reveals Toxins On Antibody-Coated Fiberoptic Probe”, Laser Focus World 28(5):83-86, 1992.
Huber, W., et al., “Direct Optical Immunosensing (Sensitivity And Selectivity)”, Sensors And Actuators B. 6:122-126, 1992.
Jorgenson, R.C., et al., “A Fiber-Optic Chemical Sensor Based On Surface Plasmon Resonance”, Sensors And Actuators B. 12, (3):213-220, 1993.
Jung, C.C., et al., “Chemical Electrode Surface Plasmon Resonance Sensor”, Sensors And Actuators B. 32(2):143-147, 1996.
Ligler, F.S., et al., “Evanescent Wave Fiber Optic Biosensor”, Proc. Biosensors, A.P.F. Turner, ed., pp. 308-315, 1992.
Rogers, Kim R., et al., “Acetylcholine Receptor Fiber-Optic Evanescent Fluorosensor”, Analytical Biochemistry 182:353-359, 1989.
Wong, R.B., et al., “Reusable Fiber-Optic-Based Immunosensor For Rapid Detection Of Imazethapyr Herbicide”, Analytica Chimica Acta, 279:141-147, 1993.

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