Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-06-07
1999-02-02
Hendricks, Keith D.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 711, 4351721, 4353201, 43525421, 43525233, 530350, 530412, 530418, 536 232, C12N 500, C12N 120, C12P 2104, C12P 120
Patent
active
058663622
ABSTRACT:
Protein aggregates obtained by a process comprising culturing a host cell that expresses a desired protein in a medium comprising an effective amount of Cu.sup.++ and wherein the desired protein forms inclusion bodies in the host cell.
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patent: 5342921 (1994-08-01), Cousens et al.
Mitraki et al., Protein Folding Intermediates and Inclusion Body Formation (1989) Biotechnology 7:690-697.
Georgiov (1988) AICHE J. 34:1233-1248 "Optimizing the Production of Recombinant Proteins in Micro-Organisms".
Strandberg et al (1991) Appl. Env. Micro. 57:1669-1674 "Factors Influencing Inclusion Body Formation in the Production of a Fused . . . ".
Cousens Lawrence S.
Tekamp-Olson Patricia
Barovsky Kenneth
Blackburn Robert P.
Chiron Corporation
Hendricks Keith D.
Hobbs Lisa J.
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