Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-03-18
1998-03-10
Shah, Mulund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514316, 514322, 514364, 546187, 546199, 548126, A61K 3141, A61K 31445, C07D27112, C07D28514
Patent
active
057261946
ABSTRACT:
Novel compounds of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, --A.dbd.B--C.dbd.D--, Ar and X have the meaning indicated in claim 1, and their salts show endothelin receptor-antagonistic properties.
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Inpadoc Abstract Services--U.S. Patent 5,378,715, EP 569,193 & WO 94279979.
Khaletsky et al., Synthesis of Piazothiole(3,4-Benzo-1,2,5-Thiodiazole) and Its Derivatives, Journal of General Chemistry, vol. 24 pp. 131-133, 1954.
Pesin et al., Chemistry of Heterocyclic Compounds, Khimiya Geterotsiklicheskikh Soedinenii, vol. 4, No. 5, pp. 587-588, 1968.
Chemical Abstract, vol. 49, No. 5, Abstract No. 3170a.
Chemical Abstract, vol. 71, No. 1, Abstract No. 3332m.
Christadler Maria
Dorsch Dieter
Mederski Werner
Osswald Mathias
Schmitges Claus
Coleman Brenda
Merck Patent Gesellschaft mit beschrankter Haftung
Shah Mulund J.
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