Elongase genes and uses thereof

Details Elongase genes and uses thereof Elongase genes and uses thereof

2005-07-05

2005-07-05

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

C435S004000, C435S069100, C435S325000, C435S410000, C435S252300, C435S252310, C435S252330, C435S254200, C435S254210, C435S320100, C435S419000, C435S254110, C435S254220, C435S254300, C435S254500, C435S254400, C435S254700, C435S254230, C435S348000, C800S295000, C536S023200

Reexamination Certificate

active

06913916

ABSTRACT:
The subject invention relates to the identification of several genes involved in the elongation of polyunsaturated acids (i.e., “elongases”) and to uses thereof. At least two of these genes are also involved in the elongation of monounsaturated fatty acids. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomogama linolenic acid (DGLA) and in the conversion of DGLA or 20:4n-3 to eicosapentaenoic acid (EPA). DGLA may be utilized in the production of polyunsaturated fatty acids, such as arachiodonic acid (AA), docosahexaenoic acid (DHA), EPA, adrenic acid, ω6-docosapentaenoic acid or ω3-docosapentaenoic acid which may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.

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