Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1996-07-01
1999-06-22
Kemmerer, Elizabeth C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
500300, C07K 14435
Patent
active
059143894
ABSTRACT:
The present invention provides compositions of isolated and purified E6 Associated Protein and fragments thereof. Also provided are nucleic acid constructs encoding E6 Associated Protein. These compositions may be employed to identify compounds which inhibit binding of high risk HPV E6 to p53. The compositions of the present invention may also be used in methods to detect the presence of high risk HPV in biological samples.
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Howley Peter M.
Huibregtse Jon M.
Scheffner Martin
Kemmerer Elizabeth C.
The United States of America as represented by the Department of
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