Chemistry: analytical and immunological testing – Optical result – With fluorescence or luminescence
Reexamination Certificate
2005-03-26
2010-11-30
Haq, Shafiqul (Department: 1641)
Chemistry: analytical and immunological testing
Optical result
With fluorescence or luminescence
C436S546000, C436S800000, C436S805000, C435S007500, C435S968000, C252S588000
Reexamination Certificate
active
07842512
ABSTRACT:
A method for photochemical reactor characterization includes an application of using dyed microspheres exposed to UV irradiation under a collimated-beam system. Particle specific fluorescence intensity measurements are conducted using samples form the collimated beam and flow-through reactor results using flow cytometry. A numerical model may be used to simulate the behavior of the reactor system to provide a particle-tracking algorithm to interrogate the flow and intensity field simulations for purposes of developing a particle specific estimate of the dose delivery. A method for measuring UV dose distribution delivery in photochemical reactors is provided that includes introducing microspheres labeled with a photochemically-active compound in a UV reactor. The labeled microspheres are harvested downstream of the irradiated zone of a UV reactor and exposed to UV irradiation under a collimated beam of UV irradiation. The method further includes quantifying a UV dose-response behavior, conducting fluorescence intensity measurement on the labeled microspheres from the UV reactor, and developing an estimate of a dose distribution delivered by a UV reactor based on the numerical deconvolution of the sum of the UV dose response behavior and fluorescent intensity of exposed microspheres.
REFERENCES:
patent: 4965350 (1990-10-01), Inoue et al.
patent: 6027855 (2000-02-01), Sokoluk et al.
“Development of a Nucleoside Analog UV Light Sensor,” by Shiyue Fang et al.; Nucleosides, Nucleotides & Nucleic Acids; vol. 22, Nos. 5-8; pp. 703-705; 2003.
“Dyed Microspheres for Quantification of UV Dose Distributions: Photochemical Reactor Characterization by Lagrangian Actinometry,” by Ernest R. Blatchely III et al.; 27 pages.
Shiyue Fang, Yousheng Guan, Ernest R. Bletchley III, Lian-Shin Lin, Cheng Yue Shen, and Donald E. Bergstrom, entitled “Development of a Nucleoside Analog UV Light Sensor,” Nucleosides, Nucleotides & Nucleic Acids, vol. 22, Nos. 5-8, pp. 703-705, 2003.
Shiyue Fang, Yousheng Guan, Ernest R. Bletchley III, Lian-Shin Lin, Cheng Yue Shen, and Donald E. Bergstrom, entitled “Development of a Nucleoside Analog UV Light Sensor,” Published in Nucleosides, Nucleotides & Nucleic Acids, vol. 22, Issue 5-8; Oct. 8, 2003; pp. 703-705; on-line Article.
W.A. Anderson, L. Zhang, S.A. Andrews, J.R. Bolton, entitled “A Technique for Direct Measurement of UV Fluence Distribution,” AWWA Water Quality Technology Conference, Proceedings, Nov. 2-6, 2003.
Zuzana Bohrerova, Gil Bohrer, S. Mohan Mohanraj, Joel Ducoste, and Karl G. Linden, entitled “Experimental Measurements of Fluence Distribution in a UV Reactor Using Fluorescent Microspheres,” Environmental Science & Technology, vol. 39, No. 22, Oct. 7, 2005, pp. 8925-8930.
Ernest R. Blatchley, III, et al., “Dyed Microspheres for Quantification of UV Dose Distributions: Photochemical Reactor Characterization by Lagrangian Actinometry,” Journal of Environmental Engineering, Nov. 2006, 1390-1403, vol. 132, No. 11.
Bergstrom Donald E.
Blatchley, III Ernest R.
Fang Shiyue
Gregori Gerald J.
Guan Yousheng
Brinks Hofer Gilson & Lione
Haq Shafiqul
Purdue Research Foundation
LandOfFree
Dyed microspheres for characterization of photochemical... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dyed microspheres for characterization of photochemical..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dyed microspheres for characterization of photochemical... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4247068