Dual oxidases as mitogenic and endocrine regulators

Details Dual oxidases as mitogenic and endocrine regulators Dual oxidases as mitogenic and endocrine regulators

2007-06-05

2007-06-05

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

C435S069100, C435S006120, C435S183000, C435S189000, C435S320100, C435S252300, C435S325000, C536S023200

Reexamination Certificate

active

10276153

ABSTRACT:
The present invention relates to new genes encoding for the production of novel proteins involved in generation of reactive oxygen intermediates and in peroxidative reactions that affect biological functions including cell division, thyroid hormone biosynthesis and tissue fibrosis. The present invention also provides vectors containing these genes, cells transfected with these vectors, antibodies raised against these novel proteins, kits for detection, localization and measurement of these genes and proteins, and methods to determine the activity of drugs to affect the activity of the proteins of the present invention.

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