Dry analytical element and method for the detection of prostatic

Details Dry analytical element and method for the detection of prostatic Dry analytical element and method for the detection of prostatic

1992-05-20

1999-11-09

Leary, Louise N.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435 4, 4352831, 4352871, 4352877, 4352878, C12Q 142, C12Q 100

Patent

active

059812060

ABSTRACT:
A dry analytical element has been prepared for the assay of prostatic acid phosphatase at a pH of from about 3 to about 6.5. The element can be a single porous spreading zone or a multilayer structure. Within the element is a relatively nonhygroscopic aromatic phosphate substrate for the analyte which produces a phenol reaction product. This product is reacted with a diazonium or tetrazolium salt, also in the element, to produce a chromophore for detection. A buffer in the element maintains it at the proper pH during the assay.

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