Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical energy applicator
Reexamination Certificate
2007-02-08
2010-11-30
Manuel, George (Department: 3762)
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Electrical energy applicator
Reexamination Certificate
active
07844345
ABSTRACT:
Medical electrical lead systems and related methods are described. The lead systems may be configured to be at least partially implanted in neural tissue of a subject, such as a brain of a subject. Some variations of the lead systems may comprise a lead body, an electrode connected to the lead body, and a bioactive agent. The electrode and/or lead body may comprise a substrate, and the bioactive agent may be supported by the substrate (e.g., by a substantial portion of the area of the substrate). Examples of bioactive agents that may be used in the lead system include antiproliferative agents, bactericidal agents, bacteriostatic agents, antiepileptic agents, and/or antifungal agents. Methods described herein may comprise coating a lead body and/or an electrode of a medical electrical lead system with at least one bioactive agent, where the lead body and the electrode are connected to each other.
REFERENCES:
patent: 3310051 (1967-03-01), Schulte
patent: 3640269 (1972-02-01), Delgado
patent: 4506680 (1985-03-01), Stokes
patent: 5092332 (1992-03-01), Lee et al.
patent: 5217028 (1993-06-01), Dutcher et al.
patent: 5255693 (1993-10-01), Dutcher et al.
patent: 5265608 (1993-11-01), Lee et al.
patent: 5496360 (1996-03-01), Hoffmann et al.
patent: 5713847 (1998-02-01), Howard, III et al.
patent: 5755758 (1998-05-01), Woloszko et al.
patent: 5834051 (1998-11-01), Woloszko et al.
patent: 5836935 (1998-11-01), Ashton et al.
patent: 5865842 (1999-02-01), Knuth et al.
patent: 6006124 (1999-12-01), Fischell et al.
patent: 6032482 (2000-03-01), Krauss
patent: 6038482 (2000-03-01), Vachon
patent: 6068853 (2000-05-01), Giannos et al.
patent: 6073048 (2000-06-01), Kieval et al.
patent: 6148231 (2000-11-01), Henley
patent: 6168801 (2001-01-01), Heil, Jr. et al.
patent: 6219577 (2001-04-01), Brown, III et al.
patent: 6227203 (2001-05-01), Rise et al.
patent: 6304787 (2001-10-01), Kuzma et al.
patent: 6330471 (2001-12-01), Higo et al.
patent: 6385491 (2002-05-01), Lindemans et al.
patent: 6497699 (2002-12-01), Ludvig et al.
patent: 6567705 (2003-05-01), Stokes et al.
patent: 6571125 (2003-05-01), Thompson
patent: 6635045 (2003-10-01), Keusch et al.
patent: 6678553 (2004-01-01), Lerner et al.
patent: 6685648 (2004-02-01), Flaherty et al.
patent: 6726678 (2004-04-01), Nelson et al.
patent: 6748653 (2004-06-01), Lindemans et al.
patent: 6931286 (2005-08-01), Sigg et al.
patent: 6944497 (2005-09-01), Stypulkowski
patent: 7010356 (2006-03-01), Jog et al.
patent: 7044942 (2006-05-01), Jolly et al.
patent: 7066904 (2006-06-01), Rosenthal et al.
patent: 7200432 (2007-04-01), Lerner et al.
patent: 7241283 (2007-07-01), Putz
patent: 7337011 (2008-02-01), Stokes et al.
patent: 2003/0236496 (2003-12-01), Samson et al.
patent: 2004/0127942 (2004-07-01), Yomtov et al.
patent: 2004/0248326 (2004-12-01), Ziaie et al.
patent: 2005/0070985 (2005-03-01), Knapp et al.
patent: 2005/0149157 (2005-07-01), Hunter et al.
patent: 2005/0246003 (2005-11-01), Black et al.
patent: 2005/0246004 (2005-11-01), Cameron et al.
patent: 2005/0277912 (2005-12-01), John
patent: 2006/0058856 (2006-03-01), Morrell
patent: 2006/0095105 (2006-05-01), Jog et al.
patent: 2006/0129204 (2006-06-01), Pless et al.
patent: 2006/0155343 (2006-07-01), Vilims
patent: 2006/0184143 (2006-08-01), Jolly et al.
patent: 2007/0060815 (2007-03-01), Martin et al.
patent: 2007/0088335 (2007-04-01), Jolly
patent: 2007/0250136 (2007-10-01), Karunasiri et al.
patent: 2008/0015540 (2008-01-01), Muni et al.
patent: 2008/0033520 (2008-02-01), Jolly
patent: 2008/0097280 (2008-04-01), Martin et al.
Anonymous. (2006). “Ommaya Reservoir,” located at <http://health.enotes.com/cancer-encyclepedia/ommaya-reservoir> , last visited on Sep. 18, 2006, six pages.
Cavuoto, J. (Jan. 2002). “Biomaterials Key Factor in Next-Generation Electrodes,”Neurotech Business Report2(1):3-5.
Christensen, J. et al. (Oct. 2001). “Plasma Concentration of Topiramate Correlates with Cerebrospinal Fluid Concentration,”Therapeutic Drug Monitoring23(5):529-535.
Craighead, H.G. (Nov. 24, 2000). “Nanoelectromechanical Systems,”Science290:1532-1535.
Doose, D.R. et al. (2002). “Topiramate: Chemistry, Biotransformation, and Pharmacokinetics,” Chapter 78, inAntiepileptic Drugs, 5thEdition, Levy, R.H. et al. eds., Lippincott Williams & Wilkins: Philadelphia, PA, pp. 727-734.
Ghosh, S. et al. (May 2000). “Electrochemical Characterization of Poly(3,4-ethylene dioxythiophene) Based Conducting Hydrogel Networks,”J. of the Electrochem. Soc. 147(5):1872-1877.
Gilmore, K. et al. (1994). “Preparation of Hydrogel/Conducting Polymer Composites,”Polymer Gels and Networks2(2):135-143.
Martin, D.C. et al. “Bio-Electronic Implantable Device Coating Applications,” in White Paper: Bioactive Conducting Polymer Coatings for Biomedical Devices, University of Michigan, four pages. (in internal database as of Aug. 30, 2006).
Olsen, R.W. (2002). “Phenobarbital and Other Barbiturates: Mechanisms of Action,” Chapter 50, inAntiepileptic Drugs, 5thEdition, Levy, R.H. et al. eds., Lippincott Williams & Wilkins: Philadelphia, PA, pp. 489-495.
Pitt, W.G. et al. (Nov. 2004). “Ultrasonic Drug Delivery—A General Review,”Expert Opinion on Drug Delivery1(1):37-56.
Rusakov, D.A. et al. (May 1, 1998). “Extrasynaptic Glutamate Diffusion in the Hippocampus:Ultrastructural Constraints, Uptake, and Receptor Activation,”The J. of Neurosci. 18(9):3158-3170.
Non-Final Office Action mailed on Sep. 8, 2009, for U.S. Appl. No. 11/704,534, filed Feb. 8, 2007, eight pages.
Non-Final Office Action mailed on Mar. 31, 2009, for U.S. Appl. No. 11/704,534, filed Feb. 8, 2007, twenty-seven pages.
Non-Final Office Action mailed on Feb. 25, 2010, for U.S. Appl. No. 11/704,534, filed Feb. 8, 2007, ten pages.
Boling C. Lance
Chao Daniel
Morrell Martha J.
Pless Benjamin D.
Tcheng Thomas K.
Manuel George
NeuroPace, Inc.
Wieland Robert N
LandOfFree
Drug eluting lead systems does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Drug eluting lead systems, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Drug eluting lead systems will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4164062