DNA methyltransferase antisense oligonucleotides

Details DNA methyltransferase antisense oligonucleotides DNA methyltransferase antisense oligonucleotides

1993-12-01

1996-11-26

Stone, Jacqueline M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 2100, A61K 4800

Patent

active

055787169

ABSTRACT:
The invention encompasses tumorigenicity-inhibiting antisense oligonucleotide sequences complementary to mRNA or double-stranded DNA that encodes mammalian DNA methyl transferase. It further encompasses methods for inhibiting tumorigenicity and pharmaceutical composition comprises the tumorigenicity-inhibiting antisense nucleotide.

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