Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...
Patent
1997-01-17
1998-08-18
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
435 6, 4353201, 435325, 4352523, 43525411, 536 232, C12N 900, C12N 1500, C12N 120, C07H 2104
Patent
active
057957576
ABSTRACT:
The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
REFERENCES:
patent: 5561054 (1996-10-01), Kron et al.
Kron, et al., "An immunodominant antigen of Brugia malayi is an asparaginyl-tRNA synthetase", FEBS Letters, 374 pp. 122-124 (1995).
Chalker, et al., "Analysis and toxic overexpression in Escherichia coli of a staphylococcal gene encoding isoleucyl-tRNA synthetase", Gene, 141, pp. 103-108 (1994).
Nilsen, et al., "Cloning and characterization of a potentially protective antigen in lymphatic filariasis", Proc. Natl. Acad. Sci. USA, 85, pp. 3604-3607 (1988).
Putzer, et. al., "Independent Genes for Two Threonyl-tRNA Synthetases in Bacillus subtilis",Journal of Bacteriology, 172, 8, pp. 4593-4602 (1990).
Fleischmann, et. al., "Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd", Science, 269, No. 5223, pp. 496-512 (1995).
Ogasawara, et. al., "Nucleotide sequence and organization of dnaB gene and neighbouring genes on the Bacillus subtilis chromosome", Nucleic Acid Research 14, No. 24 pp. 9989-9999 (1986).
Putzer, et al., "B subtilits threonyl-tRNA synthetase (thrS) gene, complete cds.", EMBL Database, Entry BSTRNASB, Accession No. M36594, (Version 8), (1992).
Chandler et al. (1996) Characterization of the Haemophilus influenza topA locus: DNA topoisomerase I is Required for Genetic Competence. Gene 169:25-31.
Hodgson John Edward
Lawlor Elizabeth Jane
Gimmi Edward R.
Hobbs Lisa J.
King William T.
Lentz Edward T.
SmithKline Beecham p.l.c.
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