DNA encoding human cytoplasmic Cu/Zn superoxide dismutase

Details DNA encoding human cytoplasmic Cu/Zn superoxide dismutase DNA encoding human cytoplasmic Cu/Zn superoxide dismutase

1994-03-16

1997-05-13

Fleisher, Mindy

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

435 691, 435325, 43525233, 43525421, 4353201, 536 232, C12N 902, C12N 1553, C12N 1566, C07H 2104

Patent

active

056291892

ABSTRACT:
Methods and compositions are provided for the production of human superoxide dismutase and a novel protocol for enhancing efficiency of expression. The gene encoding for human superoxide dismutase is isolated and inserted into a vector in conjunction with a synthetic linker which provides for enhanced efficiency in translation. E. coli strain D1210 (pSODX8) was deposited at the A.T.C.C. on Sep. 27, 1983 and given Accession No. 39453. Yeast strain 2150-2-3 (pC1/1GAPSOD) and E. coli strains D1210 (pSOD11) and D1210 (pS2OR) were deposited at the A.T.C.C. on May 9, 1984, and given Accession Nos. 20708, 39679 and 39,680, respectively.

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