Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1995-03-24
1997-07-08
Housel, James C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
4242001, 4242561, 4353201, 435 697, C07H 2102, A61K 3902, C12P 2106, C12N 1500
Patent
active
056462590
ABSTRACT:
The invention relates to novel Haemophilus adhesion proteins, nucleic acids, and antibodies.
REFERENCES:
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S. Marieke Van Ham, et al., "Cloning and expression in Escherichia coli of Haemophilus influenzae fimbrial genes establishes adherence to oropharyngeal epithelial cells", The EMBO Journal, 8(11):3535-3540, (1989).
Barenkamp, S.J., et al., "Cloning, Expression, and DNA Sequence Analysis of Genes Encoding Nontypeable Haemophilus influenzae High-Molecular-Weight Surface-Exposed Proteins Related to Filamentous Hemagglutinin of Bordetella pertussis", Infection and Immunity, 60(4):1302-1313, (1992).
St. Geme, J.W., et al., "Surface Structures and Adherence Properties of Diverse Strains of Haemophilus influenzae Biogroup aegyptius", Infection and Immunity, 59(10):3366-3371 (1991).
St. Geme, J.W., et al., "High-molecular-weight proteins of nontypable Haemophilus influenzae mediate attachment to human epithelial cells", Proc. Natl. Acad. Sci., USA, 90:2875-2879, (1993).
St. Geme, J.W., et al., "Haemophilus influenzae Adheres to and Enters Cultured Human Epithelial Cells", Infection and Immunity, 58(12):4036-4044, (1990).
St. Geme, J.W., et al., "Evidence that Surface Fibrils Expressed by Haemophilus influenzae Type b Promote Attachment to Human Epithelial Cells, " Molecular Microbiology, 15(1):77-85, (1995).
St. Geme, J.W., et al., "A Haemophilus influenzae IgA Protease-Like Protein Promotes Intimate Interaction with Human Epithelial Cells." Molecular Microbiology, 14(2):217-233 (1994).
Barenkamp Stephen J.
St. Geme, III Joseph W.
Housel James C.
Shaver Jennifer
Silva Robin M.
St. Louis University
Trecartin Richard F.
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