DNA encoding a new angiotensin II type 1 receptor subtype and it

Details DNA encoding a new angiotensin II type 1 receptor subtype and it DNA encoding a new angiotensin II type 1 receptor subtype and it

1993-03-31

1995-06-27

Draper, Garnette D.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 235, 4352402, 4352523, 43525233, C12N 1512, C12N 121, C12N 516

Patent

active

054279224

ABSTRACT:
The present invention relates to a human angiotensin II type 1 receptor protein, a recombinant DNA containing a gene which codes for said protein, a transformant carrying said DNA, production of said protein, and anti-angiotensin II substance screening methods using said transformant containing said protein.

REFERENCES:
Hahn, A. W. A., et al. (1993) Biochem. Biophys. Res. Comm. 192(3): 1260-65.
Curnow, K. M., et al. (1992) Mol. Endocrinol. 6:1113-8.
Sandberg, K., et al. (1992) J. Biol. Chem. 267:9455-58.
Bergsma et al., "Cloning and Characterization of a Human Angiotensin II Type 1 Receptor", Biochem. Biophs. Res. Commun., vol. 183, No. 3, 3 Mar. 1992, New York, pp. 989-995.
Kakar et al., "Angiotensin II Type-1 Receptor Subtype cDNAs: Differential Tissue Expression and Hormonal Regulation", Biochem. Biophs. Res. Commun., vol. 183, No. 3, 3 Mar. 1992, New York, pp. 1090-1096.
H. Furuta et al., Biochem. Biophys. Res. Commun., 183(1), 8 (1992).
R. Takayanag: et al., Biochem. Biophys. Res. Commun., 183(2), 910(1992).
T. J. Murphy et al., Nature, 351, 233 (1991).
K. Sasaki et al., Nature, 351, 230 (1991).

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