DNA coding for (Leu.sup.13) motilin

Details DNA coding for (Leu.sup.13) motilin DNA coding for (Leu.sup.13) motilin

1997-11-20

2000-01-25

Kemmerer, Elizabeth

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 536 2351, 4353201, 514 13, 530326, C07H 2104, C07K 1463

Patent

active

060180374

ABSTRACT:
A novel motilin analog peptide containing leucine instead of the usual 13th amino acid methionine, as in the naturally occurring motilin, is produced by gene recombination techniques in which several or identical genes, each coding for the novel peptide, are joined in series into a vector. The resultant recombinant DNA is introduced into Escherichia coli and the resultant transformant is cultivated. The resulting polymeric peptide can be cleaved to give the desired peptide.

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