Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-08-14
1989-04-11
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548252, 548253, C07D25704, C07D40306, A61K 3141
Patent
active
048207233
ABSTRACT:
The instant invention provides disubstituted tetrazoles that antagonizes the effect of leukotrienes C.sub.4, D.sub.4 or E.sub.4 or any combination thereof in selected tissues. The disubstituted tetrazoles are used in pharmaceutical formulations and methods of treatment of conditions caused by excessive release or production of leukotrienes C.sub.4, D.sub.4 or E.sub.4 or any combination thereof. Such conditions include an immediate hypersensitivity reaction of the type represented by asthma, or by shock or other adverse cardiovascular effects.
REFERENCES:
patent: 4661505 (1987-04-01), Marshall et al.
patent: 4663332 (1987-05-01), Carson et al.
Marshall Winston S.
Sigmund Sandra K.
Whitesitt Celia A.
Conrad Robert A.
Eli Lilly and Company
Springer David B.
Whitaker Leroy
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