Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-06-21
2011-06-21
Cheu, Jacob (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C436S518000
Reexamination Certificate
active
07964363
ABSTRACT:
A method for quantitating vitamin D metabolites directly in blood plasma or serum, without the need for prior purification of the vitamin D metabolites, comprising a digestion of the serum proteins with a serine protease such as proteinase K and sequence of steps for inhibiting the proteinase K activity in the competitive binding analysis. The advantages of this method are its high accuracy over the whole range of physiologically relevant values and that it can be easily adapted for a fully automated analysis of serum and plasma samples.
REFERENCES:
patent: WO 02/46746 (2002-06-01), None
patent: WO 03/023391 (2003-03-01), None
patent: WO 2004/063704 (2004-07-01), None
Armbruster Franz Paul
Friedl Sabine
Roth Heinz-Juergen
Schumann Claudia
Cheu Jacob
Dickstein & Shapiro LLP
Immundiagnostik AG
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