Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-10-06
1992-02-18
Fan, Jane T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D21186
Patent
active
050896245
ABSTRACT:
The present invention relates to 1,4-dihydropyridine of the formula(I) ##STR1## wherein R.sup.1 represents a phenyl group which may be substituted by one or two substituents selected from halogeno, nitro, trifluoromethyl and difluoromethoxy group, or 2,1,3-benzoxadiazole-4-yl group, R.sup.2 represents a lower alkyl or phenyl group, R.sup.3 represents a lower alkyl group and Y represents an oxygen or sulfur atom.
The compounds of the formula(I) can be employed for treatment or prevention of cardiovascular diseases.
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Meyer et al., CA 16038q and CA 16042m, vol. 78, 1973 and CA 95:6997p.
Bossert et al. CA 86:29638a.
Wehinger et al. CA 91:74480g; CA 95: 42922u; CA 99:83613c.
Meyer et al. CA 98:197957v.
Teijin Ltd. CA: 103:12337z.
Nandi et al. CA 109:104796z.
Han Byung H.
Kim Byung C.
Kim Chang S.
Kim Choong S.
Lee Bong Y.
Fan Jane T.
Yuhan Corporation
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