Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-10-30
1989-01-31
Ford, John M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546256, 546271, 514338, C07D40100, A61K 3144
Patent
active
048015989
ABSTRACT:
Compounds of the formula: ##STR1## where R is 2-substituted phenyl said substituent being chloro, bromo, cyano, methyl, methylthio, methylsulfonyl, trifluoromethyl, hydroxy, methoxy or benzyloxy; R.sup.1 is hydrogen, lower alkyl, pyridyl, thiazolyl, isoxazolyl, thiadiazdyl or thiazdylmethyl; R.sup.2 is hydrogen or lower alkyl; R.sup.3 is hydroxy, lower alkoxy, benzyloxy, amino, lower alkylamino or morpholino; Y is alkylene having two to six carbon atoms; and X is benzimidazolyl optionally substituted by lower alkyl, chloro or trifluoromethyl.
REFERENCES:
patent: 4707482 (1987-11-01), Vogel
Cooper Kelvin
Fray Michael J.
Richardson Kenneth
Ford John M.
Lumb J. Trevor
McManus James M.
Pfizer Inc.
Richardson Peter C.
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