Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1981-12-17
1983-04-05
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
42424854, 424250, 424267, 424274, 2602393T, A61K 3155, C07D41306
Patent
active
043791506
ABSTRACT:
Dibenz[b,f][1,4]oxazepine derivatives of the formula ##STR1## (wherein R.sub.1 is a hydrogen atom or a lower alkyl group; R.sub.2 is a branched lower alkyl group; R.sub.3 is a hydrogen atom, a carboxyl group, a carbamoyl group, a lower alkoxycarbonyl group, or a lower alkoxy group; R.sub.4 and R.sub.5 are each a lower alkyl group or may, when taken together with a nitrogen atom, form a heterocyclic ring; and A is a lower alkylene group) or salts thereof, a process for preparing the same and pharmaceutical compositions comprising the same are disclosed. The derivatives of the formula above are effective to prevent and treat circulatory diseases, especially angina pectoris, and therefore, useful as medicines.
REFERENCES:
patent: 3423402 (1969-01-01), Nagarajan et al.
Akima Michitaka
Aono Jinichiro
Hata Shun-ichi
Ito Kiyohiko
Koizumi Masuo
Bond Robert T.
Chugai Seiyaku Kabushiki Kaisha
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