Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-01-18
2011-01-18
Kosack, Joseph R (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S331000, C546S226000, C546S233000, C546S234000, C546S235000
Reexamination Certificate
active
07872028
ABSTRACT:
Described are diaminopropanols of which are orally active and bind to renin to inhibit its activity. They are useful in the treatment or amelioration of diseases associated with elevated. levels of renin activity or in the treatment of aspartic protease mediated disorders. Also described is a method for the use of the diaminopropanols in ameliorating or treating renin related disorders in a subject in need thereof.
REFERENCES:
patent: 7176242 (2007-02-01), John et al.
patent: 2007/0265331 (2007-11-01), Decicco et al.
patent: 2009/0018103 (2009-01-01), Baldwin et al.
patent: WO 03/006423 (2003-01-01), None
patent: WO 2006/042150 (2006-04-01), None
patent: WO 2007/070201 (2007-06-01), None
Jordan, V. C. Nature Reviews: Drug Discovery, 2, 2003, pp. 205-213.
Dörwald, F. Zaragoza. Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design, Weinheim: WILEY-VCH Verlag GmbH & Co. KGaA, 2005, Preface.
International Search Report , International Application No. PCT/US2007/008518 (Oct. 10, 2007).
Rahuel, J. et al., “Structure-Based Drug Design: The Discovery of Novel Nonpeptide Orally Active Inhibitors of Human Renin,”Chemistry&Biology, 7:493-504 (2000).
Written Opinion of the International Searching Authority, International Application No. PCT/US2007/008518 (Oct. 10, 2007).
Notification Concerning Transmittal of International Preliminary Report on Patentability, and International Preliminary Report on Patentability, International Application No. PCT/US2007/008518, mail date Oct. 8, 2008.
Baldwin John J.
Cacatian Salvacion
Claremon David A.
Dillard Lawrence W.
Flaherty Patrick T.
Coughlin Matthew P
Hamilton Brook Smith & Reynolds P.C.
Kosack Joseph R
Vitae Pharmaceuticals, Inc.
LandOfFree
Diaminopropanol renin inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Diaminopropanol renin inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Diaminopropanol renin inhibitors will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2684975