Detecting Neisseria via immobilized antibody-enzyme complex

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435176, 435810, C12Q 166, C12N 1114

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active

042542189

ABSTRACT:
A method for detecting the presence of Neisseria bacteria in a fluid sample which comprises bringing immobilized antibody specific for the enzyme 1,2-propanediol dehydrogenase which is released from such bacteria upon lysis thereof, into contact with a lysed sample, isolating the immobilized antibody or resulting immobilized antibody-enzyme complex or mixture thereof, and then testing the isolated material for enzymatic activity.

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patent: 4029756 (1977-06-01), Gaafar
patent: 4071409 (1978-01-01), Messing et al.
patent: 4140581 (1979-02-01), Weetal
patent: 4166765 (1979-09-01), Weetall

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