Derivatives of isoquinoline (and naphthalene) sulfonamides

Details Derivatives of isoquinoline (and naphthalene) sulfonamides Derivatives of isoquinoline (and naphthalene) sulfonamides

1991-09-12

1993-06-01

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540595, 544127, 544130, 544159, 544295, 544362, 544370, 544389, 544391, 544392, 544394, 546 19, 546140, 546149, 546206, 546242, 546338, 548561, 75491, C07D40112, C07D40114

Patent

active

052161501

ABSTRACT:
Novel quinoline sulfonamino derivatives having a vessel smooth muscle relaxation activity as well as a platelet agglutination inhibitory activity and inhibitory activity to protein kinase A, myosin light chain kinase, proteinkinase C, and calmodulindependent proteinkinase II, but having little action or cardio function; a process for the production of the derivatives, and a pharmaceutical composition containing the derivative.

REFERENCES:
Wagner, et al., "Chemical Abstracts", vol. 91, 1979, col. 91:108231u.
Markwardt, et al., "Chemical Abstracts", vol. 92, 1980, col. 92:176396x.
Wagner, et al., "Chemical Abstracts", vol. 96, 1982, col. 96:104709m.
Claeson, et al., "Chemical Abstracts", vol. 100, 1984, col. 100:156982r.
Strurzebecher, et al., "Die Pharmazie", vol. 42(2), 1987, p. 114.

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