Derivatives of heterocycles with 5 members, their...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S335500, C548S338100

Reexamination Certificate

active

10915001

ABSTRACT:
Thiaxozle, oxazole, imidazole, isoxazole and isoxazoline compounds of the formulawherein Het is thiazole, oxazole, imidazole, isoxazole or isoxazoline, n is an integer from 0 to 6, A is selected from the various optionally substituted aromatic radicals defined in the specification, B is hydrogen, alkyl or phenyl, R1and R2are independently hydrogen, alkyl or cycloalkyl or R1and R2taken together with the carbon atom which carries them, form a carbocycle with 3 to 7 members and Ω is —NH46R47or —OR48, R46and R47are independently hydrogen, alkyl, cycloalkyl or —(CH2)kCOOR51, R51is alkyl or haloalkyl and R48is hydrogen or alkyl having advantageous pharmacological properties which allow their use in therapeutics, for treating neurodegenerative disorders or pain.

REFERENCES:
patent: 2004/0132788 (2004-07-01), Chabrier De Lassauniere et al.
patent: WO 02/10140 (2002-02-01), None

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