Derivatives of 2-(3-phenyl-2-aminopropionyloxy)-acetic acid

Details Derivatives of 2-(3-phenyl-2-aminopropionyloxy)-acetic acid Derivatives of 2-(3-phenyl-2-aminopropionyloxy)-acetic acid

1977-09-26

1979-01-16

Helfin, Bernard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

560 39, 560 40, A61K 3124, C07C10120

Patent

active

041349911

ABSTRACT:
A compound having the general formula ##STR1## in which R represents a hydrogen atom or a hydroxyl radical, R.sub.1 represents a hydrogen atom or a methyl radical, and R.sub.2 represents a phenylethyl radical, a C.sub.1 -C.sub.16 alkyl radical, or a C.sub.6 -C.sub.16 monocyclic, polycyclic or alicyclic radical optionally bonded through a methylene radical, and its pharmaceutically acceptable acid addition salts, the formula (I) having the L-configuration when R is OH and when R and R.sub.1 are both hydrogen, and having the DL-configuration when R is hydrogen and R.sub.1 is methyl.
These compounds and salts are useful as medicaments in human and veterinary medicine for cardiovascular and/or neurological treatment.

REFERENCES:
patent: 3329711 (1967-07-01), Hegediis et al.
patent: 3983138 (1976-09-01), Saari
patent: 4051169 (1977-09-01), Saari

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