Delivery of DNA vaccines into fish by immersion

Details Delivery of DNA vaccines into fish by immersion Delivery of DNA vaccines into fish by immersion

2011-01-18

2011-01-18

Graser, Jennifer E (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S190100, C424S200100, C435S243000, C435S252100, C435S252300, C435S471000

Reexamination Certificate

active

07871629

ABSTRACT:
A method for immunizing fish against pathogenic infection is disclosed. More particularly, this invention provides a method of immunizing fish against bacterial and viral infection which comprises immersing the fish in a solution comprised of an effective amount of dead or attenuated, whole-celled recombinant bacteria, the recombinant bacteria having a eukaryotic expression vector (plasmid) incorporated therein having DNA of interest encoding at least one protein antigen for each of the pathogens, the method characterized in that the protein antigen is produced by the fish.

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