Deletion analogues of magainin peptides

Details Deletion analogues of magainin peptides Deletion analogues of magainin peptides

1988-12-09

1990-10-09

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 13, 530324, 530325, 530326, 530327, A61K 3702, C07K 708

Patent

active

049622773

ABSTRACT:
A compound comprising a deletion analogue of an amide or carboxy-terminating Magainin I of the following structural formula using the single letter amino acid code: ##STR1## and wherein at least one of amino acid residues 15 through 23 is omitted; or a deletion analogue of an amide or carboxy-terminated Magainin II of the following structural formula using the single letter amino acid code: ##STR2## and wherein at least one of amino acid residues 15 through 23 is omitted. These compounds can be effectively used as pharmaceutical compositions.

REFERENCES:
patent: 4810777 (1989-03-01), Zasloff

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