Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai
Patent
1995-09-12
1998-04-07
Dees, JoseG.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Cyclopentanohydrophenanthrene ring system doai
552636, C07J 100, A61K 31565
Patent
active
057365377
ABSTRACT:
Disclosed is the use of dehydroepiandrosterone salicylate in the treatment of skin atrophy. ##STR1## Such types skin atrophy to be treated include the thinning and/or general degradation of the dermis often characterized by a decrease in collagen and/or elastin as well as decreased number, size and doubling potential of fibroblast cells.
REFERENCES:
patent: 3879537 (1975-04-01), Van Scott et al.
patent: 3920835 (1975-11-01), Van Scott et al.
patent: 3984566 (1976-10-01), Van Scott et al.
patent: 3988470 (1976-10-01), Van Scott et al.
patent: 4105782 (1978-08-01), Yu et al.
patent: 4105783 (1978-08-01), Yu et al.
patent: 4194007 (1980-03-01), Van Scott et al.
patent: 4197631 (1980-04-01), Yu et al.et al.
patent: 4234599 (1980-11-01), Van Scott et al.
patent: 4246261 (1981-01-01), Van Scott et al.
patent: 4363815 (1982-12-01), Yu et al.
patent: 4380549 (1983-04-01), Van Scott et al.
patent: 4496556 (1985-01-01), Orentreich
patent: 4542129 (1985-09-01), Orentreich
patent: 4628052 (1986-12-01), Peat
patent: 4898694 (1990-02-01), Schwartz
patent: 4920115 (1990-04-01), Nestler et al.
patent: 4956355 (1990-09-01), Prendergast
patent: 5001119 (1991-03-01), Schwartz et al.
patent: 5028631 (1991-07-01), Schwartz et al.
patent: 5077284 (1991-12-01), Loria et al.
patent: 5091171 (1992-02-01), Yu et al.
patent: 5110810 (1992-05-01), Eich et al.
patent: 5162198 (1992-11-01), Eich et al.
patent: 5206008 (1993-04-01), Loria et al.
patent: 5227907 (1993-07-01), Loria et al.
patent: 5232917 (1993-08-01), Bolger et al.
patent: 5254343 (1993-10-01), Parah et al.
patent: 5262407 (1993-11-01), Leveque et al.
patent: 5387583 (1995-02-01), Loria et al.
patent: 5407684 (1995-04-01), Loria et al.
Adolf and Swetly, 1979, "Glucocorticoid hormones inhibit DNA synthesis and enhance interferon production in a human lymphoid cell line", Nature 282: 736-738.
Culpepper and Lee, 1987, "Glucocorticoid Regulation of Lymphokine Production by Murine T Lyphocytes", Lymphokines 13: 275-289.
Daynes et al., 1990, "Regulation of murine lymphokine production in vivo II. Dehydroepiandrosterone is a natural enhancer of interleukin 2 synthesis by helper T cells" European Journal of Immunology 20: 793-802.
Daynes et al., 1990, "Regulation of Murine Lymphokine Production In Vivo; III. The Lymphoid Tissue Microenvironment Exerts Regulatory Influences over T Helper Cell Function" J. Experimental Medicine 171: 979-996.
Daynes and Araneo, 1989, "Contrasting effects of glucocorticoids on the capacity of T cells to produce the growth factors interleukin 2 and interleukin 4", European Journal of Immunology 19: 2319-2325.
Lobo et al., 1981, "Dehydroepiandrosterone Sulfate as an indicator of Adrenal Androgen Function", Obstetrics and Gynecology 57: 69-73.
Loria et al., 1988, "Protection Against Acute Lethal Viral Infections With the Native Steroid dehydroepiandrosterone (DHEA)", Journal of Medical Virology 26: 301-314.
Loria and Padgett, 1992, "Mobilization of Cutaneous Immunity for Systemic Protection Against Infections", Annals New York Academy of Sciences 650: 363-366.
Orentreich et al., 1984, "Age Changes and Sex Differences in Serum Dehydroepiandrosterone Sulfate Concentrations throughout Adulthood", J. Clin. Endocrinol. Metab. 59(3): 551.
Regelson et al., 1988, "Hormaonal Intervention: `Buffer Hormones` or `State Dependency` The Role of Dehydroepiandrosterone (DHEA), Thyroid Hormone, Estrogen and Hypophysectomy in Aging", Annals of the New York Academy of Sciences 521: 260-73.
Gubernick Joseph
Maes Daniel H.
Badio Barbara
Dees Jose'G.
Estee Lauder Inc.
LandOfFree
Dehydroep:androsterone sailcylate useful against skin atrophy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Dehydroep:androsterone sailcylate useful against skin atrophy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Dehydroep:androsterone sailcylate useful against skin atrophy will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-13725