Dehydrocycloclausenamide, its preparation and use in treating ce

Details Dehydrocycloclausenamide, its preparation and use in treating ce Dehydrocycloclausenamide, its preparation and use in treating ce

1990-07-30

1992-03-03

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548453, 548530, 548544, C07D49708, A61K 3140

Patent

active

050933507

ABSTRACT:
Processes for the preparation of compounds of the formula ##STR1## in which R and R.sup.1 are identical or different and represent hydrogen or halogen, in the racemic form or in the form of its pure enantiomers by cyclicizing compounds of the formula ##STR2## with 2,6-lutidine or by cyclicizing compounds of the formula ##STR3## with diethyl azodicarboxylate. Compounds where R is halogen are new and are useful as cerebral therapeutics, nootropics or in the reduction of increased glutamine pyruvate transaminase in serum.

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