Cleaning compositions for solid surfaces – auxiliary compositions – Cleaning compositions or processes of preparing – For cleaning a specific substrate or removing a specific...
Reexamination Certificate
2006-02-21
2006-02-21
Gupta, Yogendra N. (Department: 1751)
Cleaning compositions for solid surfaces, auxiliary compositions
Cleaning compositions or processes of preparing
For cleaning a specific substrate or removing a specific...
C510S218000, C422S013000, C422S028000
Reexamination Certificate
active
07001873
ABSTRACT:
A surface which carries a material which is infected with prions is cleaned with an alkaline cleaning solution to remove as much proteinaceous material as possible from the surface. The cleaning agent is an alkaline cleaning agent which attacks prions remaining on the surface and which attacks prions removed from the surface during the cleaning step. After the cleaning solution is drained, a solution of surfactants, buffers, and heavy metal free corrosion inhibitors is circulated over the surface at 50°–60° C. The surfactants disperse and unclump the prion-contaminated material. A strong oxidant, preferably peracetic acid, is added to the solution to bring the peracetic acid concentration to 1,000–2,500 ppm. The peracetic acid or other strong oxidant attacks the prions, particularly the unclumped prion strands, deactivating the prions. After rinsing and drying, the surface may be wrapped in a microbe impermeable barrier and subjected to terminal sterilization, such as steam autoclaving.
REFERENCES:
patent: 5116575 (1992-05-01), Badertscher et al.
patent: 5567444 (1996-10-01), Hei et al.
patent: 2759589 (1998-08-01), None
patent: WO 98/15297 (1998-04-01), None
patent: WO 01/54736 (2001-08-01), None
MSDS data sheet for the STERIS 20®Sterilant Concentrate.
Antloga, et al. “Prion Disease and Medical Devices”, ASAIO Journal, V. 46, N. 6, 2000; pp. S69-S72 XP001092854.
Darbord, “Inactivation of Prions in Daily Medical Practice”, Biomedicine & Pharmacotherapy, V. 54, 1999 pp. 34-38 XP002228686.
Rutala, et al., “Creutzfeld-Jakob Disease : Recommendations for Disinfection and Sterilization”, Clinical Infectious Diseases, V. 32, N. 9, May 2001 pp. 1348-1356 XP008012867.
Samson, “Stérilisation du Matériel de Dermato-Chirurgie au Cabinet du Dermatologue”, Nouvelle Dermatologiques, V. 19, N. 1, 2000 pp 57-60 XP008012868.
Antloga, K., J. Meszaros, P.M. Malchesky, and G.E. McDonnell (2000). Prion Disease and Medical Devices, ASAIO J 46: S69-S72.
Baron, H., J. Safar, D. Groth, S.J. DeArmond, and S.B. Prusiner (2001). Prions,In, Disinfection, Sterilizaton and Preservation (Ed. S.S. Block), 5th edition, pp. 659-674, Lippincott, Williams & Williams, New York.
Yon, J.M. (2001), Protein Folding: A Perspective for Biology, Medicine and Biotechnology, Brazil. J. Med. Biol. Res. 34:419-435.
Antloga Kathleen M.
Kaiser Herbert J.
McDonnell Gerald E.
Scocos Jennifer A.
Fay Sharpe Fagan Minnich & McKee LLP
Gupta Yogendra N.
Petruncio John M.
Steris Inc.
LandOfFree
Decontamination of surfaces contaminated with prion-infected... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Decontamination of surfaces contaminated with prion-infected..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Decontamination of surfaces contaminated with prion-infected... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3700643