Decarboxylation process for preparing 4-(3-aminophenyl)pyridines

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546329, 546335, 544 94, C07D21516, C07D21324

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active

045323267

ABSTRACT:
4-(3-Aminophenyl)pyridines, useful in the preparation of 1-alkyl-1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic acids, are prepared by heating a 2-amino-4-(4-pyridinyl)benzoic acid at decarboxylation temperatures.

REFERENCES:
patent: 3753993 (1973-08-01), Lesher
patent: 3907808 (1975-09-01), Lesher
patent: 4118557 (1978-10-01), Lesher
Mitscher et al, J. Med. Chem., 1978, vol. 21, pp. 485-489.
Morrison et al, Organic Chem., pp. 446-447.

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