D-nor-7-ergoline derivatives having anti-Parkinson and antipsych

Details D-nor-7-ergoline derivatives having anti-Parkinson and antipsych D-nor-7-ergoline derivatives having anti-Parkinson and antipsych

1987-03-31

1989-08-29

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514256, 514389, 544333, 548336, 548421, A61K 3140, C07D20956

Patent

active

048617938

ABSTRACT:
Pharmaceutical compounds of the formula ##STR1## wherein R is H or CH.sub.3, R.sub.1 is H or OCH.sub.3, R.sub.2 is a C.sub.1 -C.sub.4 hydrocarbon group and X is an organic group. Also disclosed is a process for the preparation of these compounds. The compounds have dopamine agonist or antagonist activity.

REFERENCES:
patent: 4317912 (1982-03-01), Temperilli et al.
patent: 4742075 (1988-05-01), Hunter
Bernardi et al., Chem. Abst., vol. 108, (1988), 38179b.

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