Cyclothiocarbamate derivatives as progesterone receptor...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S653000

Reexamination Certificate

active

10601968

ABSTRACT:
The present invention provides methods of treating skin disorders includes delivering to a mammal a composition containing a compound of formula I, or tautomers thereof, in a regimen, wherein formula I is:and wherein R1-R5and Q1are defined as described herein. Specifically, methods for treating acne, hirsutism, and conditioning the skin are described. Also provided are novel PR modulators of formula II.

REFERENCES:
patent: 6355648 (2002-03-01), Fensome et al.
patent: 6407101 (2002-06-01), Collins et al.
patent: 6436929 (2002-08-01), Zhang et al.
patent: 6462038 (2002-10-01), Higuchi et al.
patent: 6521657 (2003-02-01), Fensome et al.
patent: 6566372 (2003-05-01), Zhi et al.
patent: 6583145 (2003-06-01), Fensome et al.
patent: 6964973 (2005-11-01), Zhi et al.
patent: 2002/0169198 (2002-11-01), Fensome et al.
patent: 2003/0083322 (2003-05-01), Kraemer et al.
patent: 2003/0087925 (2003-05-01), O'Neill et al.
patent: 2003/0092711 (2003-05-01), Zhang et al.
patent: 2003/0130505 (2003-07-01), Zhi et al.
patent: 2310660 (1997-09-01), None
patent: WO-85/00519 (1985-02-01), None
patent: WO 00/66555 (2000-11-01), None
patent: WO 00/66570 (2000-11-01), None
patent: WO-00/66571 (2000-11-01), None
patent: WO 00/66581 (2000-11-01), None
patent: WO-01/15108 (2001-03-01), None
patent: WO-01/77100 (2001-10-01), None
Zhang et al., “Potent Nonsteroidal Progesterone Receptor Agonists: Synthesis and SAR study of 6-Aryl Benzoxazines”, Bioorg. & Med. Chem. Lett., 12: 787-790 (Mar. 11, 2002).
Van Vloten et al., “The Effect of 2 Combined Oral Contraceptives Either Drospirenone or Cyproterone Acetate on Acne and Seborrhea”, Cutis 69: 2 (Apr. 2002).
English translation of an Office Action dated Feb. 17, 2006 issued in counterpart Taiwanese Patent Application No. 92116986.
English translation of an Office Action dated Mar. 3, 2006 issued in counterpart Chinese Patent Application No. 03815194.4.
English translation of an Office Action dated Mar. 3, 2006 provided by our agent in counterpart Chilean Patent Application No. 1280/2003.
Fensome et al., “Synthesis and Structure-Activity Relationship of Novel 6-Aryl-1,4-Dihydrobenzo[d][1,3]oxazine-2-thiones as Progrsterone Receptor Modulators Leading to the Potent and Selective Nonsteroidal Progesterone Receptor Agonists Tanaproget”, J. Med. Chem. 48:5092-5095 (2005).
Zhang et al., “Novel 6-Aryl-1,4-Dihydrobenzo[d][1,3]oxazine-2-thiones as Potent, Selective, and Orally Active Nonsteroidal Progesterone Receptor Agonists”, Bioorg. & Med. Chem. Lett., 13: 1313-1316 (2003).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Cyclothiocarbamate derivatives as progesterone receptor... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclothiocarbamate derivatives as progesterone receptor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclothiocarbamate derivatives as progesterone receptor... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3744064

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.