Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-12-06
1992-06-09
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546291, 546332, C07D213643, C07D21375, A61K 3144
Patent
active
051207524
ABSTRACT:
Certain carbocyclic aryl- and heterocyclic aryl- substituted cyclopropyl N-hydroxyureas, N-hydroxy-carboxamides, and N-acyl-N-hydroxyamines inhibit 5- and/or 12-lipoxygenase and are useful in the treatment of inflammatory disease states.
REFERENCES:
patent: 4724235 (1988-02-01), Shanklin et al.
Brooks Dee W.
Horrom Bruce W.
Mazdiyasni Hormoz
Rodriques Karen E.
Abbott Laboratories
Janssen Jerry F.
Rotman Alan L.
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