Cyclic compound having 4-pyridylalkylthio group having...

Details Cyclic compound having 4-pyridylalkylthio group having... Cyclic compound having 4-pyridylalkylthio group having...

2005-02-17

2009-06-09

Solola, Taofiq A (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S261000

Reexamination Certificate

active

07544703

ABSTRACT:
A novel cyclic compound having a 4-pyridylalkylthio group having an (un)substituted amino group introduced therein or a salt thereof. They are useful as a medicine. The cyclic compound is a compound represented by the following formula (1), which is useful for the treatment of diseases in which angiogenesis participates. In the following formula (1), ring A represents a benzene ring or a 5- or 6-membered aromatic heterocycle optionally fused with a cycloalkane ring; B represents alkylene; R1and R2each represents H, (substituted) aryl, (substituted) heterocyclic group, etc.; R3and R4each represents H, (substituted) alkyl, (substituted) cycloalkyl, -Z-R5, etc.; R5represents (substituted) alkyl, (substituted) aryl, (substituted) heterocyclic group, etc.; X and Y each represents H, etc.; Z represents —CO—, —COO—, —CONR6—, —SO2—, etc.; R6represents H, etc.; p is 0, 1, or 2; and q is 0 or 1.

REFERENCES:
patent: 6329372 (2001-12-01), Head et al.
patent: 6380214 (2002-04-01), Gant et al.
patent: 2006/0194836 (2006-08-01), Honda et al.
patent: 2350208 (2000-05-01), None
patent: 0 422 369 (1991-04-01), None
patent: 02-129173 (1990-05-01), None
patent: 02-501051 (2002-01-01), None
patent: WO 97/30035 (1997-08-01), None
patent: WO 98/35958 (1998-08-01), None
patent: WO 98/50356 (1998-11-01), None
patent: WO 00/27819 (2000-05-01), None
patent: WO 01/55114 (2001-08-01), None
patent: WO 02/066470 (2002-08-01), None
patent: WO 03/040096 (2003-05-01), None
patent: WO 2004/018414 (2004-03-01), None
patent: WO 2004/018428 (2004-03-01), None
patent: WO 2004/078723 (2004-09-01), None
King, Med Chem: Principle and Practice (1994), p. 206-208.
Nakayama Shoten,Molecular Medicine, vol. 35, special issue, “Molecular Mechanism of Symptoms and Pathologic conditions,” pp. 73-74, (1998), (Abstract).
Kyoritsu Shuppan,Protein, Nucleic Acid, Enzyme, extra number, “The Most Advanced Development of New Drugs,” pp. 1182-1187, (2000), (Abstract).
R. Ponci et al.,II Farmaco-Ed. Sc., “Derivati Piridinici Dell'Acido 2-Mercaptobenzoico Ad Attivita' Antifungina,” vol. 18, pp. 288-304, (1963), (Abstract).

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