CXC chemokines as regulators of angiogenesis

Details CXC chemokines as regulators of angiogenesis CXC chemokines as regulators of angiogenesis

1995-06-06

1999-02-16

Draper, Garnette D.

Drug, bio-affecting and body treating compositions

Lymphokine

514 2, 514 8, 514 12, A61K 3819

Patent

active

058717234

ABSTRACT:
Disclosed are various discoveries concerning the angiogenic and angiostatic properties of the CXC chemokines, including the finding that the ELR motif controls the ability of these molecules to induce angiogenesis. Aspects of the invention include, for example, the identification of IP-10, MIG and certain IL-8 analogues as angiostatic agents, and their use in inhibiting angiogenesis in various systems.

REFERENCES:
patent: 5459128 (1995-10-01), Rollins et al.
patent: 5739103 (1998-04-01), Rollins et al.

Affiliated with

Also associated with

Rating

CXC chemokines as regulators of angiogenesis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with CXC chemokines as regulators of angiogenesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and CXC chemokines as regulators of angiogenesis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2059603