Crystals of sodium cephemcarboxylate

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D50156, A61K 31545

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active

046925198

ABSTRACT:
Novel crystals of sodium 7.beta.-[2-(2-aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido]-3-[(1,2,3-th iadiazol-5-yl)thiomethyl] ceph-3-em-4-carboxylate showing characteristic peaks at interplanar spacings (d) of 9.3, 8.9, 5.3, 5.1, 4.4, 4.3 and 3.8 .ANG. in the powder X-ray diffraction pattern which are very stable and do not easily cause discoloration and decomposition.

REFERENCES:
patent: 4104470 (1978-08-01), Cise et al.
patent: 4224371 (1980-09-01), Amiord et al.
patent: 4341777 (1982-07-01), White
patent: 4399132 (1983-08-01), Curran et al.
patent: 4464367 (1984-08-01), Labeeuw
Kodama et al., ". . . Crystal Structure of a Semi-Synthetic Cephalosporim . . . ", Chem. Abst. 101:191445k (1983).
The Journal of Antibiotics, vol. 36, No. 2, pp. 179 and 180 (1983).

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