Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing
Reexamination Certificate
2008-04-01
2008-04-01
Dodson, Shelley A. (Department: 1616)
Organic compounds -- part of the class 532-570 series
Organic compounds
Oxygen containing
Reexamination Certificate
active
07351869
ABSTRACT:
Provided is a crystallization method for reducing the level of impurities in calcipotriene in which a solution of a starting calcipotriene in a first process solvent, for example THF, is combined with second process solvent, for example methyl formate, and, after cooling, calcipotriene is isolated. The method can include a slurry step for reducing the level of residual first process solvent.
REFERENCES:
patent: 4866048 (1989-09-01), Calverley et al.
patent: 5292727 (1994-03-01), Godtfredsen
patent: 5447924 (1995-09-01), Bretting
patent: 5716945 (1998-02-01), Grue-Sorensen
patent: 5763426 (1998-06-01), Hansen et al.
patent: 5824313 (1998-10-01), Daynes et al.
patent: 5994332 (1999-11-01), Calverley
patent: 6162801 (2000-12-01), Kita
patent: 6197982 (2001-03-01), Bretting
patent: 6231875 (2001-05-01), Sun et al.
patent: 6310226 (2001-10-01), Calverley et al.
patent: 6399797 (2002-06-01), von Daehne et al.
patent: 2002/0004063 (2002-01-01), Zhang
patent: 2002/0022052 (2002-02-01), Dransfield
patent: 2002/0071852 (2002-06-01), Deckers et al.
patent: 2002/0106337 (2002-08-01), Deckers et al.
patent: 2003/0166226 (2003-09-01), Shapiro et al.
patent: WO-94/15912 (1994-07-01), None
patent: WO 03 060094 (2003-07-01), None
PCT International Search Report—PCT/US03/37138.
Martin J. Caverley, “Synthesis of MC 903, a biologically active vitamin D metabolite analogue”, Tetrahedron, vol. 43, No. 20, 1987, pp. 4609-4616.
Caverley, M. J. and Bretting, C., “1-alpha-24S-dihydroxy-26, 27-cyclo-22-yne-vitamin D3: the side chain tirple bond analogue of MC 903 (calcipotriol)”, Bioorganic and Medicinal Chemistry Letters, vol. 3, n. 9, 1993, pp. 1841-1844.
Maimon Asher
Schwartz Anchel
Dodson Shelley A.
Kenyon & Kenyon LLP
Teva Pharmaceutical Industries Ltd
LandOfFree
Crystallization method for purification of calcipotriene does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Crystallization method for purification of calcipotriene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystallization method for purification of calcipotriene will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2765944