Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Reexamination Certificate
2004-03-17
2009-12-15
Tate, Christopher R (Department: 1651)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
C435S041000, C435S132000, C435S155000, C424S094400
Reexamination Certificate
active
07632665
ABSTRACT:
The present application relates to a reaction system in which chemically valuable compounds can be obtained in high enantiomer concentrations with the aid of a coupled enzymatically operating transformation process. The coupled enzymatic reaction system comprises a cofactor-dependent enzymatic transformation of an organic compound and an enzymatic regeneration of the cofactor, wherein the reaction system operates in aqueous solution with an amount of substrate above the solubility limit thereof. In the preferred embodiments, an alcohol dehydrogenase is the cofactor-dependent enzyme, and the regeneration of the cofactor (e.g. NADH or NADPH) is acheved by means of formate dehydrogenase.
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Chamouleau Francoise
Drauz Karlheinz
Gröger Harald
Hagedorn Chad
Hummel Werner
Evonik Degussa GmbH
Kosar Aaron J
Law Office of Michael A. Sanzo, LLC
Sanzo Michael A.
Tate Christopher R
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