Conversion of mocimycin to antibiotic X-5108 and intermediates

Details Conversion of mocimycin to antibiotic X-5108 and intermediates Conversion of mocimycin to antibiotic X-5108 and intermediates

1976-12-10

1978-09-05

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 17, C07H 308

Patent

active

041122160

ABSTRACT:
The present invention relates to the conversion of the antibiotic mocimycin to the antibiotic known as X-5108 by treating mocimycin with a methylating agent after first protecting the 4-hydroxy functional group of the pyridone moiety, followed by subjecting the protecting group containing ester of X-5108 to mild basic hydrolysis whereby antibiotic X-5108 is obtained.

REFERENCES:
berger et al. "The Journal of Antibiotics," vol. XXVI, No. 1, 1973, pp.15-22.
Berger et al. "Chem. Abst." vol. 78, 1973 pp.109, 258(b).

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