Controlled release of macromolecular polypeptides

Details Controlled release of macromolecular polypeptides Controlled release of macromolecular polypeptides

1986-05-23

1990-10-09

Thexton, Matthew A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, 514964, 424 78, 424 89, 424 92, 424 851, 424 852, 424 856, 424 858, 424 854, A61K 3112, A61K 4700

Patent

active

049620916

ABSTRACT:
An active agent delivery system for the controlled administration of macromolecular polypeptides which comprises a micro-suspension of water-soluble components in a polylactide matrix.

REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 3976071 (1976-08-01), Sadek
patent: 4225581 (1980-09-01), Kreuter et al.
patent: 4293539 (1981-10-01), Ludwig
patent: 4419340 (1983-12-01), Yolles
patent: 4512972 (1985-04-01), Schmidt-Ruppin
patent: 4613500 (1986-09-01), Suzuki et al.
patent: 4637931 (1987-01-01), Schmitz
patent: 4678809 (1987-07-01), Phillips
Journal of Bioengineering, vol. 1, pp. 25-52 (1986).
Journal of Pharmaceutical Sciences, vol. 73, pp. 1294-1297 (1984).
American Journal of Obstetrics and Gynecology, vol. 140, pp. 799-806 (1978).
Contraception, vol. 13, pp. 375-384 (1976).

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