Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-01-31
2006-01-31
Raymond, Richard L. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S217120, C514S227500, C514S237800, C514S239500, C514S247000, C514S248000, C514S252120, C514S255010, C514S275000, C514S310000, C514S313000, C514S329000, C514S331000, C514S352000, C514S357000, C514S371000, C514S377000, C514S419000, C514S426000, C514S427000, C514S447000, C514S456000, C514S459000, C514S470000, C514S471000, C544S058200, C544S059000, C544S168000, C544S169000, C544S382000, C544S400000
Reexamination Certificate
active
06992081
ABSTRACT:
The present invention is directed toward substituted hydroxyethylene compounds of formulas (XII) (XIII), and (XIV)useful in treating Alzheimer's disease and other similar diseases.
REFERENCES:
patent: 4224179 (1980-09-01), Schneider
patent: 4231877 (1980-11-01), Yamauchi et al.
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4247411 (1981-01-01), Vanlerberghe et al.
patent: 4394448 (1983-07-01), Szoka, Jr. et al.
patent: 4399216 (1983-08-01), Axel et al.
patent: 4522811 (1985-06-01), Eppstein et al.
patent: 4616088 (1986-10-01), Ryono et al.
patent: 4636491 (1987-01-01), Bock et al.
patent: 4665193 (1987-05-01), Ryono et al.
patent: 4668770 (1987-05-01), Boger et al.
patent: 4673567 (1987-06-01), Jizomoto
patent: 4676980 (1987-06-01), Segal et al.
patent: 4736866 (1988-04-01), Leder et al.
patent: 4749792 (1988-06-01), Natarajan et al.
patent: 4753788 (1988-06-01), Gamble
patent: 4814270 (1989-03-01), Piran
patent: 4816567 (1989-03-01), Cabilly et al.
patent: 4870009 (1989-09-01), Evans et al.
patent: 4880781 (1989-11-01), Hester, Jr. et al.
patent: 4897355 (1990-01-01), Eppstein et al.
patent: 5010182 (1991-04-01), Brake et al.
patent: 5122523 (1992-06-01), Morishima et al.
patent: 5142056 (1992-08-01), Kempe et al.
patent: 5145684 (1992-09-01), Liversidge et al.
patent: 5162538 (1992-11-01), Voges et al.
patent: 5175281 (1992-12-01), McCall et al.
patent: 5250565 (1993-10-01), Brooks et al.
patent: 5364934 (1994-11-01), Drayna et al.
patent: 5374652 (1994-12-01), Buzzetti et al.
patent: 5376542 (1994-12-01), Schlegal
patent: 5387742 (1995-02-01), Cordell
patent: 5441870 (1995-08-01), Seubert et al.
patent: 5461067 (1995-10-01), Norbeck et al.
patent: 5475138 (1995-12-01), Pal et al.
patent: 5481011 (1996-01-01), Chen et al.
patent: 5482947 (1996-01-01), Talley et al.
patent: 5502061 (1996-03-01), Hui et al.
patent: 5502187 (1996-03-01), Ayer et al.
patent: 5508294 (1996-04-01), Vazquez et al.
patent: 5510349 (1996-04-01), Talley et al.
patent: 5510388 (1996-04-01), Vazquez et al.
patent: 5516784 (1996-05-01), Bennett et al.
patent: 5521219 (1996-05-01), Vazquez et al.
patent: 5545640 (1996-08-01), Beaulieu et al.
patent: 5593846 (1997-01-01), Schenk et al.
patent: 5602169 (1997-02-01), Hewawasam et al.
patent: 5602175 (1997-02-01), Talley et al.
patent: 5604102 (1997-02-01), McConlogue et al.
patent: 5610190 (1997-03-01), Talley et al.
patent: 5612486 (1997-03-01), McConlogue et al.
patent: 5625031 (1997-04-01), Webster et al.
patent: 5631405 (1997-05-01), Pal et al.
patent: 5639769 (1997-06-01), Vazquez et al.
patent: 5648511 (1997-07-01), Ng et al.
patent: 5663200 (1997-09-01), Bold et al.
patent: 5703129 (1997-12-01), Felsenstein et al.
patent: 5708004 (1998-01-01), Talley et al.
patent: 5720936 (1998-02-01), Wadsworth et al.
patent: 5721130 (1998-02-01), Seubert et al.
patent: 5733882 (1998-03-01), Carr et al.
patent: 5744346 (1998-04-01), Chrysler et al.
patent: 5753652 (1998-05-01), Fässler et al.
patent: 5760064 (1998-06-01), Vazquez et al.
patent: 5760076 (1998-06-01), Vazquez et al.
patent: 5766846 (1998-06-01), Schlossmacher et al.
patent: 5807870 (1998-09-01), Anderson et al.
patent: 5807891 (1998-09-01), Bold et al.
patent: 5811633 (1998-09-01), Wadsworth et al.
patent: 5827891 (1998-10-01), Dressman et al.
patent: 5830897 (1998-11-01), Vazquez et al.
patent: 5831117 (1998-11-01), Ng et al.
patent: 5847169 (1998-12-01), Nummy et al.
patent: 5849911 (1998-12-01), Fässler et al.
patent: 5850003 (1998-12-01), McLonlogue et al.
patent: 5863902 (1999-01-01), Munoz et al.
patent: 5872101 (1999-02-01), Munoz et al.
patent: 5877015 (1999-03-01), Hardy et al.
patent: 5877399 (1999-03-01), Hsiao et al.
patent: 5886046 (1999-03-01), Hirschmann et al.
patent: 5912410 (1999-06-01), Cordell
patent: 5922770 (1999-07-01), Peschke et al.
patent: 5935976 (1999-08-01), Bold et al.
patent: 5942400 (1999-08-01), Anderson et al.
patent: 5962419 (1999-10-01), McDonald et al.
patent: 5965588 (1999-10-01), Vazquez et al.
patent: 6001813 (1999-12-01), Gyorkos et al.
patent: 6013658 (2000-01-01), Lau et al.
patent: 6022872 (2000-02-01), Vazquez et al.
patent: 6045829 (2000-04-01), Liversidge et al.
patent: 6051684 (2000-04-01), McDonald et al.
patent: 6060476 (2000-05-01), Vazquez et al.
patent: 6150344 (2000-11-01), Carroll et al.
patent: 6153652 (2000-11-01), Wu et al.
patent: 6191166 (2001-02-01), Audia et al.
patent: 6221670 (2001-04-01), Cordell et al.
patent: 3610593 A1 (98) (1987-10-01), None
patent: 3721 855 A1 (93) (1988-09-01), None
patent: 40 03 575 (1991-08-01), None
patent: 0 036776 A2 (471) (1981-09-01), None
patent: 0 073 657 B1 (476) (1983-03-01), None
patent: 0 117 058 B1 (473) (1984-08-01), None
patent: 0 117 060 A2 (472) (1984-08-01), None
patent: 0 173 441 A1 (557) (1986-05-01), None
patent: 0 209 897 A2 (90) (1987-01-01), None
patent: 0 212 903 B1 (100) (1987-03-01), None
patent: 0 264 106 B1 (101) (1988-04-01), None
patent: 0 274 259 A2 (89) (1988-07-01), None
patent: 0 320 205 A2 (102) (1989-06-01), None
patent: 0 337 714 (8) (1989-10-01), None
patent: 0 362 179 A2 (449) (1990-04-01), None
patent: 0 372 537 A2 (96) (1990-06-01), None
patent: 0 437 729 A2 (21) (1991-07-01), None
patent: 0 609 625 A1 (567) (1994-08-01), None
patent: 0 652 009 A1 (709) (1995-05-01), None
patent: 2 203 740 A (544) (1988-10-01), None
patent: 2 211 504 A (475) (1989-07-01), None
patent: 7-126286 (97) (1995-05-01), None
patent: WO 87/02986 (551) (1987-05-01), None
patent: WO 87/04349 (10) (1987-07-01), None
patent: WO 87/05330 (454) (1987-09-01), None
patent: WO 89/00161 (15) (1989-01-01), None
patent: WO 89/01488 (12) (1989-02-01), None
patent: WO 89/05859 (453) (1989-06-01), None
patent: WO 90/13646 (452) (1990-11-01), None
patent: WO 91/00360 (451) (1991-01-01), None
patent: WO 92/00750 (537) (1992-01-01), None
patent: WO 92/17490 (14) (1992-10-01), None
patent: WO 92/20373 (455) (1992-11-01), None
patent: WO 93/02057 (11) (1993-02-01), None
patent: WO 93/08829 (450) (1993-05-01), None
patent: WO 93/17003 (7) (1993-09-01), None
patent: WO 94/04492 (848) (1994-03-01), None
patent: WO 95/06030 (839) (1995-03-01), None
patent: WO 96/35414 (999) (1996-11-01), None
patent: WO 97/30072 (22) (1997-08-01), None
patent: WO 98/22597 (170) (1998-05-01), None
patent: WO 98/29401 (562) (1998-07-01), None
patent: WO 98/33795 (546) (1998-08-01), None
patent: WO 98/38167 (987) (1998-09-01), None
patent: WO 98/50342 (550) (1998-11-01), None
patent: WO 99/41266 (568) (1999-08-01), None
patent: WO 99/54293 (635) (1999-10-01), None
patent: WO 00/17369 (169) (2000-03-01), None
patent: WO 00/47618 (364) (2000-08-01), None
patent: WO 00/56335 (314) (2000-09-01), None
patent: WO 00/61748 (302) (2000-10-01), None
patent: WO 00/69262 (272) (2000-11-01), None
patent: WO 00/77030 (256) (2000-12-01), None
patent: WO 01/00663 (159) (2001-01-01), None
patent: WO 01/00665 A2 (20) (2001-01-01), None
patent: WO 01/10387 A2 (443) (2001-02-01), None
patent: WO 01/19797 A2 (381) (2001-03-01), None
patent: WO 01/23533 A2 (289) (2001-04-01), None
patent: WO 01/29563 A1 (479) (2001-04-01), None
patent: WO 01/51659 A2 (790) (2001-07-01), None
Abbenante, et al.,Biochemical and Biophysical Research Communications,2000, 268,pp. 133135 Inhibitors of β-Amyloid Formation Based on the β-Secretase Cleavage Site [439].
Alterman et al.,J. Med. Chem,1998, 41, 3782-3792 Design and Synthesis of New Potent C2-Symmetric HIV-1 Protease Inhibitors. Use of L-Mannaric Acid as a Peptidomimetic Scaffold [868].
Arnblard et al.,J. Med. Chem.,1999, 42:20, pp. 4193-4201 Synthesis and Characterization fo Bradykinin B2Receptor Agonists Containing Constrained Dipeptide Mimics [730 ].
Arrowsmith et al.,Tetrahedron Letters,1987, 28:45, pp. 5569-5572 Amino-Alcohol Dipeptide Analogues: A Synthesis of a Versatile Isostere for the Development of Proteinase Inhibitors [584].
Askin et al.,The Journal of Organic Chemistry,1992, 57:10, pp. 2771-2773 Highly Disastrous Alkylations of Chiral Amide Enolates: New Routes to Hydroxyethylene Dipeptide Isostere Inhibitors of HIV-1 Protease [561].
Balicki et al.,Synth. Comm.,1993, 23(22),
Fang Lawrence
Gailunas Andrea
Hom Roy
John Varghese
Mamo Shumeye
Elan Pharmaceuticals Inc.
Hulbert & Berghoff LLP
McDonnell Boehnen
Raymond Richard L.
Tucker Zachary G.
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