Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reexamination Certificate
2005-11-15
2005-11-15
Davis, Zinna Northington (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
C562S426000, C562S465000
Reexamination Certificate
active
06964983
ABSTRACT:
This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, and methods of using them as therapeutic agents for treating or preventing disipidemia, hypercholesteremia, obesity, eating disorders, hyperglycemia, atherosclerosis, hypertriglyceridemia, hyperinsulinemia and diabetes in a mammal as well as methods of supressing appetite and modulating leptin levels in a mammal. The present invention also discloses methods for making the disclosed compounds.
REFERENCES:
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patent: WO 01/00603 (2001-01-01), None
patent: WO 01/16120 (2001-03-01), None
patent: WO 02/100403 (2002-12-01), None
T. Gordon et al., The American Journal of Medicine, 1977;62:707-714.
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W.R. Oliver et al., PNAS, vol. 98, pp. 5306-5311, (2001).
S.M. Berge et al., “Pharmaceutical Salts”, Journal of Pharmaceutical Sciences, 1977;66:1-19.
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Auerbach Bruce J.
Bratton Larry D.
Filzen Gary F.
Geyer Andrew G.
Trivedi Bharat K.
Ashbrook Charles W.
Davis Zinna Northington
Sherwood Michelle A.
Warner-Lambert Company LLC
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