Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-04-11
2011-11-29
Seaman, D M (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
Reexamination Certificate
active
08067434
ABSTRACT:
Compounds active on Ret are described, as well as methods of using such compounds. Also described are crystal structures of Ret surrogates that were determined using X-ray crystallography. The use of such Ret surrogate crystals and structural information can, for example, be used for identifying molecular scaffolds and for developing ligands that bind to and modulate Ret and for identifying improved ligands based on known ligands.
REFERENCES:
patent: 2234705 (1941-03-01), Normington et al.
patent: 2413258 (1946-12-01), Soday et al.
patent: 4150949 (1979-04-01), Smith
patent: 4568649 (1986-02-01), Bertoglio-Matte
patent: 4626513 (1986-12-01), Burton et al.
patent: 4727395 (1988-02-01), Oda et al.
patent: 5120782 (1992-06-01), Hubsch et al.
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5338849 (1994-08-01), Festal et al.
patent: 5426039 (1995-06-01), Wallace et al.
patent: 5432177 (1995-07-01), Baker et al.
patent: 5434049 (1995-07-01), Okano et al.
patent: 5449614 (1995-09-01), Danos et al.
patent: 5474935 (1995-12-01), Chatterjee et al.
patent: 5556752 (1996-09-01), Lockhart et al.
patent: 5576319 (1996-11-01), Baker et al.
patent: 5580859 (1996-12-01), Felgner et al.
patent: 5631236 (1997-05-01), Woo et al.
patent: 5632957 (1997-05-01), Heller et al.
patent: 5658775 (1997-08-01), Gilboa
patent: 5681959 (1997-10-01), Bishop et al.
patent: 5700637 (1997-12-01), Southern
patent: 5700809 (1997-12-01), Leeson et al.
patent: 5712285 (1998-01-01), Curtis et al.
patent: 5721118 (1998-02-01), Scheffler
patent: 5744305 (1998-04-01), Fodor et al.
patent: 5747276 (1998-05-01), Hoch et al.
patent: 5763198 (1998-06-01), Hirth et al.
patent: 5770456 (1998-06-01), Holmes
patent: 5800992 (1998-09-01), Fodor et al.
patent: 5807522 (1998-09-01), Brown et al.
patent: 5830645 (1998-11-01), Pinkel et al.
patent: 5840485 (1998-11-01), Lebl et al.
patent: 5856174 (1999-01-01), Lipshutz et al.
patent: 5877007 (1999-03-01), Housey
patent: 5959098 (1999-09-01), Goldberg et al.
patent: 5965452 (1999-10-01), Kovacs
patent: 6013440 (2000-01-01), Lipshutz et al.
patent: 6022963 (2000-02-01), McGall et al.
patent: 6025155 (2000-02-01), Hadlaczky et al.
patent: 6045996 (2000-04-01), Cronin et al.
patent: 6048695 (2000-04-01), Bradley et al.
patent: 6054270 (2000-04-01), Southern
patent: 6090912 (2000-07-01), Lebl et al.
patent: 6096718 (2000-08-01), Weitzman et al.
patent: 6107478 (2000-08-01), Pedersen et al.
patent: 6110456 (2000-08-01), During
patent: 6110458 (2000-08-01), Freeman et al.
patent: 6113913 (2000-09-01), Brough et al.
patent: 6117681 (2000-09-01), Salmons et al.
patent: 6161776 (2000-12-01), Byles
patent: 6178384 (2001-01-01), Kolossvåry
patent: 6235769 (2001-05-01), Clary
patent: 6243980 (2001-06-01), Bronstein et al.
patent: 6258606 (2001-07-01), Kovacs
patent: 6261776 (2001-07-01), Pirrung et al.
patent: 6277489 (2001-08-01), Abbott et al.
patent: 6277628 (2001-08-01), Johann et al.
patent: 6288234 (2001-09-01), Griffin
patent: 6294330 (2001-09-01), Michnick et al.
patent: 6310074 (2001-10-01), Depreux et al.
patent: 6545014 (2003-04-01), Verner
patent: 6858860 (2005-02-01), Hosono et al.
patent: 7259165 (2007-08-01), Bernotas et al.
patent: 7361763 (2008-04-01), Arnold et al.
patent: 7361764 (2008-04-01), Arnold et al.
patent: 7452993 (2008-11-01), Arnold et al.
patent: 7498342 (2009-03-01), Ibrahim et al.
patent: 7504509 (2009-03-01), Ibrahim et al.
patent: 7582637 (2009-09-01), Arnold et al.
patent: 7601839 (2009-10-01), Arnold et al.
patent: 7626021 (2009-12-01), Arnold et al.
patent: 2001/0008765 (2001-07-01), Shinoke et al.
patent: 2001/0012537 (2001-08-01), Anderson et al.
patent: 2001/0014448 (2001-08-01), Chappa et al.
patent: 2001/0014449 (2001-08-01), Nerenberg et al.
patent: 2001/0016322 (2001-08-01), Caren et al.
patent: 2001/0018642 (2001-08-01), Balaban et al.
patent: 2001/0019827 (2001-09-01), Dawson et al.
patent: 2003/0003004 (2003-01-01), Stones et al.
patent: 2004/0002534 (2004-01-01), Lipson et al.
patent: 2004/0022534 (2004-02-01), Amano et al.
patent: 2004/0077595 (2004-04-01), Cheng et al.
patent: 2004/0142864 (2004-07-01), Bremer et al.
patent: 2004/0167030 (2004-08-01), Bernotas et al.
patent: 2005/0085463 (2005-04-01), Weiner et al.
patent: 2005/0154014 (2005-07-01), Bloxham et al.
patent: 2005/0164300 (2005-07-01), Artis et al.
patent: 2005/0170431 (2005-08-01), Ibrahim et al.
patent: 2005/0256151 (2005-11-01), Salom et al.
patent: 2006/0035898 (2006-02-01), Arnold et al.
patent: 2006/0058339 (2006-03-01), Ibrahim et al.
patent: 2006/0058340 (2006-03-01), Ibrahim et al.
patent: 2007/0032519 (2007-02-01), Zhang et al.
patent: 2007/0049615 (2007-03-01), Ibrahim et al.
patent: 2007/0287711 (2007-12-01), Arnold et al.
patent: 2008/0167338 (2008-07-01), Spevak et al.
patent: 2008/0188514 (2008-08-01), Wu et al.
patent: 2009/0005356 (2009-01-01), Blaney et al.
patent: 2009/0076046 (2009-03-01), Zhang et al.
patent: 2009/0143352 (2009-06-01), Arnold et al.
patent: 2009/0306056 (2009-12-01), Arnold et al.
patent: 24 13 258 (1975-10-01), None
patent: 0154734 (1985-09-01), None
patent: 0465970 (1991-06-01), None
patent: 1 057 826 (2000-12-01), None
patent: 870768 (2002-05-01), None
patent: 1 267 111 (2002-12-01), None
patent: 1 749 829 (2007-02-01), None
patent: 02292143 (1996-02-01), None
patent: 02292145 (1996-02-01), None
patent: 02298198 (1996-08-01), None
patent: 2299581 (1996-10-01), None
patent: 6135946 (1994-05-01), None
patent: 10-130269 (1998-05-01), None
patent: 15073357 (2003-03-01), None
patent: WO93/13099 (1993-07-01), None
patent: WO 94/14808 (1994-07-01), None
patent: WO94/20459 (1994-09-01), None
patent: WO 94/20497 (1994-09-01), None
patent: WO95/04742 (1995-02-01), None
patent: WO 95/07910 (1995-03-01), None
patent: WO 95/28387 (1995-10-01), None
patent: WO 96/00226 (1996-01-01), None
patent: WO96/11929 (1996-02-01), None
patent: WO96/05200 (1996-04-01), None
patent: WO 96/17958 (1996-06-01), None
patent: WO 96/18738 (1996-06-01), None
patent: WO 97/46313 (1997-12-01), None
patent: WO 97/46558 (1997-12-01), None
patent: WO97/49703 (1997-12-01), None
patent: WO 98/06433 (1998-02-01), None
patent: WO98/22457 (1998-05-01), None
patent: WO98/47899 (1998-10-01), None
patent: WO 99/00386 (1999-01-01), None
patent: WO 99/09217 (1999-02-01), None
patent: WO99/51231 (1999-10-01), None
patent: WO 99/51232 (1999-10-01), None
patent: WO 99/51233 (1999-10-01), None
patent: WO 99/51234 (1999-10-01), None
patent: WO 99/51595 (1999-10-01), None
patent: WO 99/51596 (1999-10-01), None
patent: WO 99/51773 (1999-10-01), None
patent: WO 00/09162 (2000-02-01), None
patent: WO00/12074 (2000-03-01), None
patent: WO00/12514 (2000-03-01), None
patent: WO 00/29411 (2000-05-01), None
patent: WO00/53582 (2000-09-01), None
patent: WO 00/64898 (2000-11-01), None
patent: WO00/71537 (2000-11-01), None
patent: WO00/75139 (2000-12-01), None
patent: WO/2004/009600 (2001-01-01), None
patent: WO01/09121 (2001-02-01), None
patent: WO 01/24236 (2001-04-01), None
patent: WO 01/29036 (2001-04-01), None
patent: WO-01/46196 (2001-06-01), None
patent: WO 01/60822 (2001-08-01), None
patent: WO01/62255 (2001-08-01), None
patent: WO 01/62255 (2001-08-01), None
patent: WO01/98299 (2001-12-01), None
patent: WO02/00657 (2002-01-01), None
patent: WO02/18346 (2002-03-01), None
patent: WO02/083175 (2002-10-01), None
patent: WO02/085896 (2002-10-01), None
patent: WO02/102783 (2002-12-01), None
patent: WO03/000258 (2003-01-01), None
patent: WO-03/003004 (2003-01-01), None
patent: WO03/006459 (2003-01-01), None
patent: WO03/008422 (2003-01-01), None
patent: WO03/011868 (2003-02-01), None
patent: WO 03/020698 (2003-03-01), None
patent: WO03/028724 (2003-04-01), None
patent: WO03/037862 (2003-05-01), None
patent: WO03/051838 (2003-06-01), None
patent: WO-03/064413 (2003-08-01), None
patent: WO03/068221 (2003-08-01), None
patent: WO03/082289 (2003-10-01), None
patent: WO03/082868 (2003-10-01), None
patent: WO03/082869 (2003-10-01), None
patent: WO03/087087 (2003-10-01), None
patent: WO03/101990 (2003-12-01), None
patent: WO2004/009600 (2004-01-01), None
patent: WO-2004/016609 (2004-02-01), None
pate
Artis Dean Richard
Bremer Ryan
Habets Gaston
Hurt Clarence R.
Ibrahim Prabha
Foley & Lardner LLP
Plexxikon Inc.
Rahmani Niloofar
Reiter Stephen E.
Seaman D M
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