Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-04-19
2011-04-19
Kosack, Joseph R (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S234500, C514S235200, C514S323000, C514S217070, C514S238800, C514S235500, C514S313000, C514S318000, C514S341000, C514S314000, C514S233800, C514S340000, C514S234800, C514S228200, C540S597000, C544S128000, C544S127000, C544S139000, C544S131000, C544S124000, C544S119000, C544S137000, C544S135000, C544S133000, C544S058600, C546S159000, C546S160000, C546S194000, C546S275100, C546S169000, C548S338100
Reexamination Certificate
active
07928133
ABSTRACT:
The invention provides a method for modulating the activity of the hedgehog signaling pathway. In particular, the invention provides a method for inhibiting aberrant growth states resulting from phenotypes such as Ptc loss-of-function, hedgehog gain-of-function, smoothened gain-of-function or Gli gain-of-function, comprising contacting a cell with a sufficient amount of a compound of Formula I.
REFERENCES:
patent: 6444687 (2002-09-01), Stamford et al.
patent: 2008/0161345 (2008-07-01), Ungashe et al.
patent: WO0144201 (2001-06-01), None
patent: WO2004091610 (2004-10-01), None
patent: WO2006/050351 (2006-05-01), None
Cheng Dai
Gao Wenqi
Han Dong
Jiang Jiqing
Jin Qihui
Coughlin Matthew P
Genomics Institute of the Novartis Research Foundation
IRM LLC
Kosack Joseph R
Reid Scott W.
LandOfFree
Compounds and compositions as hedgehog signaling pathway... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compounds and compositions as hedgehog signaling pathway..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds and compositions as hedgehog signaling pathway... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2719071