Compound useful in cholesterol assay procedures

Details Compound useful in cholesterol assay procedures Compound useful in cholesterol assay procedures

1977-08-17

1980-02-19

Padgett, Benjamin R.

Compositions

Nonreactive analytical, testing, or indicating compositions

23230B, 2603972, 424 2, 424 3, 424238, 424242, 424243, G01N 3316, G09K 300, G01N 3114

Patent

active

041894006

ABSTRACT:
A compound is disclosed herein which is water soluble and is useful in assay procedures for measuring serum cholesterol. In one embodiment, the compound comprises a cholesterol ester having the general formula R.sub.1 -R.sub.2 -[Cholesterol Base], in which R.sub.1 is a water soluble, nonionic surfactant and R.sub.2 is a dicarboxyl group bonded by ester linkages to R.sub.1 and to the cholesterol. In an alternate embodiment the compound comprises a pregnenolone derivative having the general formula R.sub.3 -[Pregnenolone Base]-R.sub.4. A compound in accordance with the present invention is useful by itself or in combination with blood serum as a standard or reference material for cholesterol assay procedures.

REFERENCES:
patent: 3260648 (1966-07-01), Fox
patent: 3274062 (1966-09-01), Lou
patent: 3764556 (1973-10-01), Kuchmak et al.
patent: 3853465 (1974-12-01), Rush et al.
patent: 3859047 (1975-01-01), Klein
patent: 3891573 (1975-06-01), Stary et al.
patent: 3955925 (1976-05-01), Proksch et al.
patent: 4011045 (1977-03-01), Donderman

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